Protein Info for DvMF_2269 in Desulfovibrio vulgaris Miyazaki F

Annotation: DNA polymerase III, subunits gamma and tau (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 688 TIGR02397: DNA polymerase III, subunit gamma and tau" amino acids 5 to 359 (355 residues), 408.9 bits, see alignment E=1e-126 PF13177: DNA_pol3_delta2" amino acids 20 to 178 (159 residues), 161.1 bits, see alignment E=5.8e-51 PF00004: AAA" amino acids 42 to 176 (135 residues), 51.8 bits, see alignment E=2.9e-17 PF12169: DNA_pol3_gamma3" amino acids 233 to 368 (136 residues), 110.7 bits, see alignment E=1.3e-35

Best Hits

KEGG orthology group: K02343, DNA polymerase III subunit gamma/tau [EC: 2.7.7.7] (inferred from 100% identity to dvm:DvMF_2269)

Predicted SEED Role

"DNA polymerase III subunits gamma and tau (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQU3 at UniProt or InterPro

Protein Sequence (688 amino acids)

>DvMF_2269 DNA polymerase III, subunits gamma and tau (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSNAPLTARYRPQTFAEVAGQETVKAILSRAAAEDRVAPAYLFSGTRGVGKTTIARILAK
ALNCEKAPTGEPCNTCEQCRKVVMGNHVDVVEIDGASNRGIEDARRLREAIGYAPMEGRY
KVFIIDEAHMLTREAFNALLKTLEEPPPRVTFVLATTEPHKFPVTIISRCQHFTFKRLPE
NELEAHLTGVLTREGQDFDPAAVRLIARRAAGSVRDSMSLLGQVLALGGDRLTVEGARGV
LGLAGQELFFEVMQALASQDCVAVSAVVRDLLDKGVDIGFFLRELASTWRNLFMLRQAGE
AALPALDLPEEEARQWLEWAPKFEITHIHACWQMTLEGQRRVLTSLEPAMALELLLLNLA
MLPRLVSLEQLSRGGGAGPAGGRGMPGGVGGVGGGPAGGSGMPGGGAGGHGSMPPRQGGY
GGYGAQSGQSGQPGQFGQSGQSGESFPQAQPPQGRYPGPGQVRPQAASSASSMSSSSGVP
GAPGMQPAGGFPRPERAAPAAAPAPSRGGSDTSLPWDDVPYPAPGGAAFGDAAIGGTSSV
PGAPDSVASASDTPDTLGAPDAPAPHEDGTWVGFVQYCVERNGEGGSSLSMLRQAQGHCA
DGRLTVSTRSSTLYNQLSVPGNEALLVARARAYFGTDVRVEVLPPTTRIKTPSELRAEAE
RHPAVSLLREQFGATMLSCRPLADGRLQ