Protein Info for DvMF_2252 in Desulfovibrio vulgaris Miyazaki F

Annotation: DEAD/DEAH box helicase domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 950 990 PF00270: DEAD" amino acids 134 to 296 (163 residues), 146.8 bits, see alignment E=8e-47 PF04851: ResIII" amino acids 136 to 281 (146 residues), 27.9 bits, see alignment E=3e-10 PF00271: Helicase_C" amino acids 335 to 443 (109 residues), 100.9 bits, see alignment E=7.5e-33

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 98% identity to dvm:DvMF_2252)

Predicted SEED Role

"Superfamily II DNA and RNA helicases"

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQS6 at UniProt or InterPro

Protein Sequence (990 amino acids)

>DvMF_2252 DEAD/DEAH box helicase domain protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MTHDPRLEGDAHSAADTDETPSSAPAAADVPAPAVADTPGTTAADTPGTPPPVAASDAPD
EGTPPEISDPAPAIPADTAALAALADDEDPALRLAAEITRIDEPEDALPPVTLANLPPMM
QEAAARAGWTNLMPVQTHALPYIFAKRDLMVQSRTGSGKTGAFLLPLLERLSPDEPAVQA
LILVPTRELALQVEYEARVLFEGTGLNVAAVYGGVGYGKQMDALRDGAHLVVGTPGRVLD
HLLRRTMNLDRIRALVFDEADRMLSIGFYPDMKEIQRYLPKRRISAYLFSATYPPHVLNL
AGEFLSEPRMLSLSHQQVHVAQTQHLYCETKPMDKDRALVRIIESENPTAAIIFCNTKAN
VHYVTAVLQGFGYNADELSADLTQAKREQVLGSLRKGGVRFLVATDVAARGIDIPDLSHV
ILYEPPEDRESYIHRAGRTGRAGSAGTVISLVDIIQKLELQRIAKHYKIDIQHRPTPDDE
SVARIAGDRLTALLEARLRARTGLERERQQRFAPLARALAGDDEQLALLAMLLDQYYQES
LHAAPPMPATAPAPRQDRRREERRDDRRDERRDERRDDRRDEREGREARRRDRDRRDERR
DERRDERKDERREERAPAAAATDAPSGSDSPEQHAEQREDDQAPREGRRRSRRGRGRKRR
RDAEARAAQEAGQAADATQDHADDMTDDADDAWDGGMTAAPEAPEAPKTLSEAPRQRREA
RPAKTDAPAASAASTEDEAEDAPAGKPAKAKPARPARGKAAKAAQATESAPDSADSDAPD
APSSTEETAEAKPARGARRGRGKAEAASPEKGKAASAGKAASGGKPRAKAPERDEDEDDG
MPLLLEDYLSEDDDRLDDVRGSAPSVGSVFGQRLPTGAKAQAQPAQSARPSQSSRSGGKA
AAKPKEAPKAAPAPVQPMLTQALEGSGAFDDEFDEDFDDQPGGNDASDAATGNAATPAKR
RRRRRRKKPAGAAPEGADAGTAHHAEADAE