Protein Info for DvMF_2127 in Desulfovibrio vulgaris Miyazaki F

Annotation: metallo-beta-lactamase family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF13483: Lactamase_B_3" amino acids 5 to 196 (192 residues), 81.7 bits, see alignment E=9.4e-27 PF12706: Lactamase_B_2" amino acids 25 to 197 (173 residues), 94.5 bits, see alignment E=1e-30 PF00753: Lactamase_B" amino acids 25 to 122 (98 residues), 30.9 bits, see alignment E=3.9e-11

Best Hits

Swiss-Prot: 71% identical to Y151_DESAG: UPF0173 metal-dependent hydrolase Dde_0151 (Dde_0151) from Desulfovibrio alaskensis (strain G20)

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_2127)

Predicted SEED Role

"metallo-beta-lactamase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQF1 at UniProt or InterPro

Protein Sequence (246 amino acids)

>DvMF_2127 metallo-beta-lactamase family protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MQYSLTWHGHANFQISCDGANGLANVLIDPFFEGNPSASTPWSDIAPPDLVLVTHDHGDH
VGQAVQICNASGALLGCIVGTAQRLLDEGLRPGLLLNSIGFNIGGTVTHKGVSVTMTQAF
HSSESGAPVGYIVTMPGGFTFYHAGDTGIFASMELWGRLHSIDLAMLPIGGTFTMDARQA
AMASAMLRTRSVVPMHWGTFPVLEQNTERFREQLRNHAPDCRLFDMKPGDTITLDMGEDG
RGCAYC