Protein Info for DvMF_2125 in Desulfovibrio vulgaris Miyazaki F

Annotation: DEAD/DEAH box helicase domain protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 531 PF00270: DEAD" amino acids 28 to 191 (164 residues), 173.5 bits, see alignment E=4.7e-55 PF00271: Helicase_C" amino acids 229 to 338 (110 residues), 111.7 bits, see alignment E=3.5e-36 PF03880: DbpA" amino acids 453 to 523 (71 residues), 86.8 bits, see alignment E=1.2e-28

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to dvm:DvMF_2125)

Predicted SEED Role

"DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)" (EC 3.6.4.13)

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQE9 at UniProt or InterPro

Protein Sequence (531 amino acids)

>DvMF_2125 DEAD/DEAH box helicase domain protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
METLRFEELSLSKEILKAIEEMGFEETSPIQALAIPHILEGRDVIGQAQTGTGKTAAFGI
PLLERIDPREKDIQGIILCPTRELAIQVAEELTQLASRKRGLYVLPVYGGQPIDRQFKAL
RRGAQVVVGTPGRVMDHMERGTINLSTVRMAVLDEADEMLDMGFRDDIEHILGQVPGEAQ
TVFFSATMPPAILDMAQRFLKTPEFLKVTQKQVTVPSIEQIYYEVRPFQKLEALCRVLDL
YNPKRAIVFCSTKRGVDELTQHLQGRGYQADGLHGNLNQSQRDRVMARFRSNGIEILVAT
DVAARGIDVDDVEAVVNYDIPNAVEHYVHRIGRTGRAGRSGRAFTFVSGRDFYKLRDIKK
FTKAHIVQHQVPTSSDVATVKTNQLLAEVRRHIEAGELEKYTDIVESFLDEDVTTVDMAA
ALLKLLMRRELGDAVPGGEKTPAGTGAEPGMVRLFLNVGRKMRVTARDIVGAIAGETGIP
GRMIGAIDIRDRVSFVEVPADYAQEVISVMNGNQIRGFRLGVEPATPRDRE