Protein Info for DvMF_2082 in Desulfovibrio vulgaris Miyazaki F

Annotation: DNA polymerase III, beta subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 388 PF00712: DNA_pol3_beta" amino acids 1 to 112 (112 residues), 66.6 bits, see alignment E=2.3e-22 PF02768: DNA_pol3_beta_3" amino acids 298 to 375 (78 residues), 33.8 bits, see alignment E=2.7e-12

Best Hits

KEGG orthology group: K02338, DNA polymerase III subunit beta [EC: 2.7.7.7] (inferred from 100% identity to dvm:DvMF_2082)

Predicted SEED Role

"DNA polymerase III beta subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQA6 at UniProt or InterPro

Protein Sequence (388 amino acids)

>DvMF_2082 DNA polymerase III, beta subunit (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MFLRIQKEDVIEGLQKAASIIPAKTGAAYLRSIWLKAENGSLSVLATDSNIEFRGAYAAE
IEQPGLAGVQGRAFVDLLRKLPGGQITLKLDGESGNLLIEQGRRKYKLPVNDSVWFQNFS
EFPADGSVMWSGDYLQELIDRIAFCISDEDAVEAIACLSLKPGAQNAIEACGLNGHQFAM
LRFTHDELMAMLPPEGILIQKKYLGELKKWLGTDEVELNISEKRLHFRTGDGKETFSLPL
SYYQYPDYMNFLAKLSADSVSRLELPRKDAMDALDRLLIFNTDSNRCTYFDLDGNGGGGD
VVLSAQGQDVGSATETLEATYSGDIKKIAFPTRNLIEIMGHYRSERLGLTLTGSEGPCGL
TGSDDSEYTVIIMPMKIVEETYYSEEEV