Protein Info for DvMF_1972 in Desulfovibrio vulgaris Miyazaki F

Annotation: CRISPR-associated protein Cas5 family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 221 PF09704: Cas_Cas5d" amino acids 7 to 212 (206 residues), 146.6 bits, see alignment E=5.2e-47 TIGR02593: CRISPR-associated protein Cas5" amino acids 7 to 46 (40 residues), 55.4 bits, see alignment 3.8e-19 TIGR01876: CRISPR-associated protein Cas5, subtype I-C/DVULG" amino acids 8 to 220 (213 residues), 191.8 bits, see alignment E=1.6e-60

Best Hits

Swiss-Prot: 54% identical to CAS5D_MANSM: CRISPR pre-crRNA endoribonuclease Cas5d (cas5d) from Mannheimia succiniciproducens (strain MBEL55E)

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1972)

Predicted SEED Role

"CRISPR-associated protein, Cas5d family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DQ51 at UniProt or InterPro

Protein Sequence (221 amino acids)

>DvMF_1972 CRISPR-associated protein Cas5 family (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSFGVSLAVWGEYACFTRPEFKTERVSYDVITPSAARGLLEAVYWKPAIAWMVDRIRVLN
PIRFDSVRRNEVGCKIPLGAVTAAMKDPERPLGILVEDERRQRATLLLRDVRYVIDAHFE
ARDEDGRNTAKHRDIFLRRAARGQCFHMPYLGCREFPASFQLVEGDPPHPHESLLEERDL
GWMLHDLDYGPDGERQPRFFRACMQDGVIEVPPLRSLEVRA