Protein Info for DvMF_1909 in Desulfovibrio vulgaris Miyazaki F

Annotation: CDP-glucose 4,6-dehydratase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 369 TIGR02622: CDP-glucose 4,6-dehydratase" amino acids 6 to 356 (351 residues), 458.6 bits, see alignment E=7.1e-142 PF04321: RmlD_sub_bind" amino acids 10 to 164 (155 residues), 35.5 bits, see alignment E=1.9e-12 PF01370: Epimerase" amino acids 11 to 238 (228 residues), 112.2 bits, see alignment E=8.3e-36 PF01073: 3Beta_HSD" amino acids 12 to 194 (183 residues), 38.7 bits, see alignment E=1.8e-13 PF16363: GDP_Man_Dehyd" amino acids 12 to 230 (219 residues), 112.1 bits, see alignment E=1.2e-35 PF02719: Polysacc_synt_2" amino acids 53 to 223 (171 residues), 44.5 bits, see alignment E=3.5e-15

Best Hits

KEGG orthology group: K01709, CDP-glucose 4,6-dehydratase [EC: 4.2.1.45] (inferred from 100% identity to dvm:DvMF_1909)

Predicted SEED Role

"Similar to CDP-glucose 4,6-dehydratase (EC 4.2.1.45)" (EC 4.2.1.45)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.1.45

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DPY8 at UniProt or InterPro

Protein Sequence (369 amino acids)

>DvMF_1909 CDP-glucose 4,6-dehydratase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MFADAYRGRKVLVTGHTGFKGSWLTAWLLQLGAEVAGLSVDVPTSPANFDELGLGARITD
IRADIRDRAAVCKAVADFAPEVVFHLAAQALVRKSYDDPAATIEANAMGTLNILEAVRCA
PSVQAVVCITSDKCYRNDEWVWGYRETDHLGGEDPYSASKGCAEIIAHSYFRSFFRNGVR
CATTRAGNVIGGGDWAADRIVPDCARAWAEGKAVQIRSPWATRPWQHVLEPLSGYLWLGA
KLLLNEQGPFPLSGEAYNFGPAADVNNNVAEVVDALAPYWPGFASEMDRAGQAGMKECTL
LKLCCDKSLAYLGWQATLNFVETIRFTAEWYRAFYAPQGAARPDMYAFTMNQIAEYSDKA
AAKGLAWAR