Protein Info for DvMF_1864 in Desulfovibrio vulgaris Miyazaki F

Annotation: phosphate acetyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13500: AAA_26
  • amino acids 4 to 186 (183 residues), 90.9 bits, E=1.6e-29
• PF07085: DRTGG
  • amino acids 219 to 332 (114 residues), 97.6 bits, E=5.4e-32
• PF01515: PTA_PTB
  • amino acids 378 to 694 (317 residues), 448 bits, E=3.3e-138
• TIGR00651: phosphate acetyltransferase
  • amino acids 393 to 694 (302 residues), 428.6 bits, E=7.7e-133

Best Hits

Swiss-Prot: 87% identical to PTA_DESVH: Phosphate acetyltransferase (pta) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K13788, phosphate acetyltransferase [EC: 2.3.1.8] (inferred from 100% identity to dvm:DvMF_1864)

Predicted SEED Role

"Phosphate acetyltransferase (EC 2.3.1.8)" in subsystem Ethanolamine utilization or Fermentations: Lactate or Fermentations: Mixed acid or MLST or Propanediol utilization or Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate or Threonine anaerobic catabolism gene cluster (EC 2.3.1.8)

MetaCyc Pathways

• ethanolamine utilization (5/5 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (15/19 steps found)
• lactate fermentation to acetate, CO₂ and hydrogen (Desulfovibrionales) (7/8 steps found)
• pyruvate fermentation to acetate and lactate II (4/4 steps found)
• pyruvate fermentation to acetate I (3/3 steps found)
• pyruvate fermentation to acetate VII (3/3 steps found)
• superpathway of acetate utilization and formation (3/3 steps found)
• acetate and ATP formation from acetyl-CoA I (2/2 steps found)
• sulfoacetaldehyde degradation I (2/2 steps found)
• acetylene degradation (anaerobic) (4/5 steps found)
• pyruvate fermentation to acetate and (S)-lactate I (3/4 steps found)
• heterolactic fermentation (13/18 steps found)
• pyruvate fermentation to acetate II (2/3 steps found)
• pyruvate fermentation to acetate IV (2/3 steps found)
• L-threonine degradation I (4/6 steps found)
• superpathway of fermentation (Chlamydomonas reinhardtii) (6/9 steps found)
• mixed acid fermentation (11/16 steps found)
• (S)-propane-1,2-diol degradation (3/5 steps found)
• sulfolactate degradation II (2/4 steps found)
• superpathway of L-threonine metabolism (12/18 steps found)
• purine nucleobases degradation II (anaerobic) (16/24 steps found)
• methanogenesis from acetate (3/6 steps found)
• superpathway of sulfolactate degradation (3/6 steps found)
• superpathway of taurine degradation (3/6 steps found)
• superpathway of Clostridium acetobutylicum acidogenic fermentation (5/9 steps found)
• superpathway of N-acetylneuraminate degradation (14/22 steps found)
• superpathway of L-alanine fermentation (Stickland reaction) (4/9 steps found)
• acetyl-CoA fermentation to butanoate (2/7 steps found)
• (S)-lactate fermentation to propanoate, acetate and hydrogen (6/13 steps found)
• superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (8/17 steps found)
• L-lysine fermentation to acetate and butanoate (2/10 steps found)
• gallate degradation III (anaerobic) (2/11 steps found)
• superpathway of methanogenesis (3/21 steps found)
• superpathway of L-lysine degradation (5/43 steps found)

KEGG Metabolic Maps

• Propanoate metabolism
• Pyruvate metabolism
• Taurine and hypotaurine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.8

Sequence Analysis Tools

See B8DMG4 at UniProt or InterPro

Protein Sequence (704 amino acids)

>DvMF_1864 phosphate acetyltransferase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MANNLYITATESKSGKSAVVLGMMQLLLRDIRKVAFFRPIINRPVTDAVDHDTNLILTHF
NLDIPVADTYAYSLQDARELINNGQHATLLENILKKYKQLEDSYDFVLCEGTDFLGKDAA
FEFDLNADIAANLGCPVMVVANGQQKTAHEIVASTQLTIDLLDEKGLDIVAAVINRASVT
DAERDVVISSLECKVNCSNPLAVYVVPEEPTLGKPTMGDVKKWLNAQVLYGHGRMDTLVD
DYVIAAMQIGNFLDYVTPGCLVITPGDRSDIILTGLATRLSGAYPDISGMLLTGGIQPAP
NVHRLIEGWTGVPIPILSVKDHTYKTIQTLNELYGKIEPDNERKINTALGLFERSVDSQE
LGRRLINRKSSRITPMMFEFNLIERAKQNRMRIVLPEGVEERILRAADILARREVADIIL
LGDADKVGAKVSELGIALDGVQIIQPNLSPKFEEYAQAYFELRKHKGVSIERARDTMNDV
TYFGTMMVHKGDAEGMVSGSINTTAHTIRPAFEFIKTKPGFSIVSSVFLMCLKDRVLAFG
DCAVNPNPTAEQLAEIAINSAHTARIFGIEPRVAMLSYSTGSSGKGADVEKVIEATRIAK
ERAPELLLEGPLQYDAAIDMDVARTKLPGSQVAGQATVFIFPDLNTGNNTYKAVQRAAGA
VAIGPVLQGLNKPVNDLSRGCTVPDIVNTVAITAIQAQAEKGLI