Protein Info for DvMF_1776 in Desulfovibrio vulgaris Miyazaki F

Annotation: GCN5-related N-acetyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 898 PF02629: CoA_binding" amino acids 12 to 103 (92 residues), 28.4 bits, see alignment E=5.9e-10 PF13380: CoA_binding_2" amino acids 15 to 140 (126 residues), 69.2 bits, see alignment E=1.1e-22 PF13607: Succ_CoA_lig" amino acids 157 to 294 (138 residues), 179.1 bits, see alignment E=9.2e-57 PF13549: ATP-grasp_5" amino acids 484 to 705 (222 residues), 264.3 bits, see alignment E=1.9e-82 PF00583: Acetyltransf_1" amino acids 786 to 875 (90 residues), 32.3 bits, see alignment E=2.6e-11

Best Hits

KEGG orthology group: K09181, hypothetical protein (inferred from 100% identity to dvm:DvMF_1776)

Predicted SEED Role

"Protein acetyltransferase" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DM77 at UniProt or InterPro

Protein Sequence (898 amino acids)

>DvMF_1776 GCN5-related N-acetyltransferase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MATQSSLEQMFKPNSVAVIGATSTPGEPGCVIMENLMAGTFLGPVLPVNETGEAVAGMPG
HTAIDTLPLTPDLAIICSPPETIPGYIEELGKRGTRAAVIMSRGFFRFDRERREVQKAAL
LQAAQRWGVRVLGPNCLGFITPSVGVNASLAPREALPGKVAFLSQSDSLFTSVLDWATSK
GIGFSHFIALGDRYDVHFNDVLDYLNGDVNTRAVLLYIETIDSARRFMSAARALARNKPV
LVIKAGRSEAAAAAAAAHSGMLLGADEVYDAAFRRAGMLRVADIDAMFDTVETLALAKPL
KGDRLAILTNGGSPGFLATDALLQGRGKLAELSDETCQALDNELGRDWSYWNPLIVRSSA
DGAMYAKALQILLDDRGVDAVLVMHVPTFSMPSDDVAGAVIEVARRSRKPVLTSWLGIDD
AAGARRKFAAAGVPSHFTPDNAVRAFLNMVEYRRNQDTLMETPPSLPEAFNPDVTAARMV
VNDALEAKRMLLTPAEAHAVLTAYGIPVAETRHVKTPREAVAAAAEIGYPVALKVESPDV
PRTSLAGGVALNLASDEEVMDAALSTANNVCDQVPGARMEGYAVQRMCRLAGAHELAVET
ATDPVFGPIIRFGQGGSMAEVLADRQTALPPLNMGLAQELVSRTRVYRLLRGSGHKAHVN
LDAVRLLLCKVSQLIIDIPEIFELEIDPLFVDADGVVALDAHMRIAWSTTTGTDQLAIRP
YPRELEECVALRDGRHVDLLPIRPEDEPEHWEFVESLSAEDKRFRFFGNVAKLPRAEMVK
LTQIDYDREMAFIAKGPDNDGVMRTLGVVRAMVSTDNSEAEFAVAVRSDLKRQGLGKLLM
QKIIRYCKARGTKRIVGAALGDNKSMAELARSVGFIVSKDYDEDIWQLDLPLEDGKGE