Protein Info for DvMF_1736 in Desulfovibrio vulgaris Miyazaki F

Annotation: serine/threonine protein kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 653 PF07714: PK_Tyr_Ser-Thr" amino acids 175 to 233 (59 residues), 30.5 bits, see alignment 3.6e-11 PF00069: Pkinase" amino acids 183 to 306 (124 residues), 74.9 bits, see alignment E=1e-24 PF07603: DUF1566" amino acids 540 to 647 (108 residues), 53 bits, see alignment E=6.3e-18

Best Hits

KEGG orthology group: K08884, serine/threonine protein kinase, bacterial [EC: 2.7.11.1] (inferred from 100% identity to dvm:DvMF_1736)

Predicted SEED Role

"serine/threonine protein kinase"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DM37 at UniProt or InterPro

Protein Sequence (653 amino acids)

>DvMF_1736 serine/threonine protein kinase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MRIGRYEVCGLLGRGGMGAVYKVRQPVTGRIAALKLLRPADALADLSDPSDMDDLRRRFL
HEAQVMAALDHPHVAAVWDVDVAPAGTLRLPSGDDFCPPPDAWDGGEGNPLVEAAGAVEV
AGDTRGADTAAPEDCDPERDRTARVARFGDLPFFVMEYYCLNLGLLIGESYRVEAPTRRL
PLPRACRYAAQTLDALARMHHAGVIHRDVKPFNIMVTAEDDVKLIDFGLSRLRGEAGALS
RLRGETGAQARLGGEVQRLPRGVKVGSPYYAAPEQERDPDGVDGRADLFAVGVMLFRMLT
GVLPTDEAFGGRIPRISKRHAELDAAWDDFFARAMARDPAQRFADARTMAAELDALVAAW
RQRVDAVCLLPEGDGAPGDAGVAGDADNGNDATPDGVRRAAHGSLSDTAGRTAANVIVPG
QVRSAPVKVMPRHSRALFGLDELWRPAGVFAPSSLASGAGRNGGPACGLLPGLPVPNLPA
PGASSTGSRRPDAATPGASAVPGGAGPVASDASGSPEPAAPADLPASPIDLAALVAYQPA
TGLLWQRGGSEWGLPLTEAHAHVAELNAARFAGFDDWRLPTVDEVCTLLAPPPEGGGHCV
PPVLDPIPDPLWTADRKSFTAGWFVSASMGFVGWQDDTCRFHVRVVRTVREVR