Protein Info for DvMF_1612 in Desulfovibrio vulgaris Miyazaki F

Annotation: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 820 TIGR02166: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family" amino acids 15 to 810 (796 residues), 1173.7 bits, see alignment E=0 PF04879: Molybdop_Fe4S4" amino acids 56 to 112 (57 residues), 43 bits, see alignment 5.5e-15 PF00384: Molybdopterin" amino acids 116 to 572 (457 residues), 222.9 bits, see alignment E=9.8e-70 PF01568: Molydop_binding" amino acids 692 to 804 (113 residues), 100.8 bits, see alignment E=6.9e-33

Best Hits

Swiss-Prot: 58% identical to DMSA_ECOLI: Dimethyl sulfoxide reductase DmsA (dmsA) from Escherichia coli (strain K12)

KEGG orthology group: K07306, anaerobic dimethyl sulfoxide reductase subunit A [EC: 1.8.99.-] (inferred from 100% identity to dvm:DvMF_1612)

MetaCyc: 58% identical to dimethyl sulfoxide reductase subunit A (Escherichia coli K-12 substr. MG1655)
DIMESULFREDUCT-RXN [EC: 1.8.5.3]

Predicted SEED Role

No annotation

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.8.5.3

Use Curated BLAST to search for 1.8.5.3 or 1.8.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DS21 at UniProt or InterPro

Protein Sequence (820 amino acids)

>DvMF_1612 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MPAGTGPQDCAARGLDRRTFLKWCALLGGAAMLPGGLAGLCPAVAEAAGGGEPQDFVWSS
CNVNCGSRCVLRAMVRDGAIVRMDTDNLGSDDYGTHQIRACLRGRAMRQRVYAPERLKYP
MLRTGKRGEAAFRRATWDEALDVIAAKMKDIKERYGNEAFYLNYGTGNLGSVMSKSWPTD
QTPITRLMNCYGGYLNHYNTYSTAQIATSMPYLYGGGLGNALSDIVNSKLVVLFGNNPAE
TRMSGGGVVYDIQRAKRESNVRVIVIDPRYTDTAVAVADEWIPIRPATDAALAAGIAYVL
FTEGMADRSFMDTYCVGHDEAHLPEGVPAGSSYEAYITGKGPDGVAKTPGWASAICGVPV
DTIVRLAREIGTAKPCCISQGWGPQRHHNGETNCRAIAVLAALTGNVGISGGNTGAREGG
YSIPFPGFPTLKNPVAASISFFLWTDAIVRGPEMTAERDGVRGVPRLNVPVKFIWNYAGN
ALINQHSDINRTAQILSDDTKCEMIVVVENFMTPSARFADVLLPAVTNLEENDFAHQGST
AEMGYVVFAQKAIEPLFESRSVYDMCADIAERLGVREQYTEGRTRDQWLQKILTDARQKL
PDLPATLEEAWKLGVYKVRNPGKPFVAYKAFRDDPVANPLATPSGRIEIFSKRLWDIGHK
WELPAGERITALPEYDEAAEGQGDPLRKKYPLQLVTHHYKQRTHSTYGNVPWLKEAAPQT
VWVNPLDAADRGLAHGDMVRVFNDRGATVLPVKVTPRIMPGIISIPQGAWYTPGAGGTDF
GGSANILTSLRPSPLAKGNPQHTTLVEMARHSGGSHANAS