Protein Info for DvMF_1518 in Desulfovibrio vulgaris Miyazaki F

Annotation: NADH dehydrogenase (quinone) (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 648 transmembrane" amino acids 6 to 23 (18 residues), see Phobius details amino acids 31 to 53 (23 residues), see Phobius details amino acids 59 to 83 (25 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 125 to 145 (21 residues), see Phobius details amino acids 165 to 182 (18 residues), see Phobius details amino acids 188 to 206 (19 residues), see Phobius details amino acids 218 to 236 (19 residues), see Phobius details amino acids 256 to 275 (20 residues), see Phobius details amino acids 285 to 304 (20 residues), see Phobius details amino acids 324 to 346 (23 residues), see Phobius details amino acids 353 to 372 (20 residues), see Phobius details amino acids 378 to 401 (24 residues), see Phobius details amino acids 422 to 444 (23 residues), see Phobius details amino acids 458 to 478 (21 residues), see Phobius details amino acids 507 to 528 (22 residues), see Phobius details amino acids 553 to 573 (21 residues), see Phobius details amino acids 628 to 647 (20 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 119 to 154 (36 residues), 37.7 bits, see alignment 1.5e-13 PF00361: Proton_antipo_M" amino acids 182 to 458 (277 residues), 184.5 bits, see alignment E=2.6e-58

Best Hits

KEGG orthology group: K05903, NADH dehydrogenase (quinone) [EC: 1.6.99.5] (inferred from 100% identity to dvm:DvMF_1518)

Predicted SEED Role

"Energy-conserving hydrogenase (ferredoxin), subunit A" in subsystem Energy-conserving hydrogenase (ferredoxin) or NiFe hydrogenase maturation

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.99.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DLU0 at UniProt or InterPro

Protein Sequence (648 amino acids)

>DvMF_1518 NADH dehydrogenase (quinone) (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MLDTLVFGSVVFPLLAALAVYFVRGDAARNIIVPVSVAITAAAALGLAGLGSFSYSPQAI
LGISLNGLITVLDFALLGFIFLIALRMGNLLIMGLTVLQVLGMVYLDFFLMDHGTQVTGF
YADSLSLTMVLIISIVGGLICFYGLGYMKEHEEHLHLAKSRQPRFFFFMLLFLGAMNGLV
LANNLSWMYFFWEVTTLCSFMLIGHDGTDEAKTNATRALWMNMAGGVAFVAALMFLQKST
GTLSVQDILAKSAAPGMKTAALLLPMAFLCFAGFTKAAQVPFQSWLCGAMVAPTPVSALL
HSSTMVKAGVYLVIRMAPAYQGTMLSAAVAIFGAFTFIAASALAVGQSNGKKVLAYSTIA
NLGLIIACAGINTSAAIAAAVMLIIFHAISKALLFLCVGAIEQKIGSRDIEAMRGLFKVM
PRTAVITVIGIVTMMLPPFGMLLAKWMALESAATATAAMPPLVIMLALGSALTVLFWARW
AGVMLGSTVPGENPPTEHQPFSVRLPLLLLAGGAVGLSLLSPFVYSMLVAPATALYAKAT
AYTVSMGVFENNAGVFAVYPLFLLLGVGFVYALRAAKKVGPEAASLPYMGGSQRVENGKI
GFNGPMNGFVETAAGNYYMESLFGESKLSKSINVIAIVLLAVMLGGVL