Protein Info for DvMF_1505 in Desulfovibrio vulgaris Miyazaki F

Annotation: protein of unknown function DUF140 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 430 transmembrane" amino acids 185 to 203 (19 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 255 to 278 (24 residues), see Phobius details amino acids 311 to 331 (21 residues), see Phobius details amino acids 336 to 357 (22 residues), see Phobius details amino acids 368 to 390 (23 residues), see Phobius details amino acids 410 to 428 (19 residues), see Phobius details PF13466: STAS_2" amino acids 63 to 136 (74 residues), 34.4 bits, see alignment E=2e-12 TIGR00056: ABC transport permease subunit" amino acids 179 to 426 (248 residues), 232.7 bits, see alignment E=2.9e-73 PF02405: MlaE" amino acids 213 to 423 (211 residues), 247.1 bits, see alignment E=1.4e-77

Best Hits

KEGG orthology group: K02066, putative ABC transport system permease protein (inferred from 100% identity to dvm:DvMF_1505)

Predicted SEED Role

"ABC-type transport system involved in resistance to organic solvents, permease component USSDB6A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DLS7 at UniProt or InterPro

Protein Sequence (430 amino acids)

>DvMF_1505 protein of unknown function DUF140 (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MRETVPPFREPTLKGDYRRPDPDAHAGQHEPGLVCTPAASCVEPGPSDGMDDGMGRGARE
LVLTFSGVWDVASIGRMTARLLRRCAEVGNACSVQGDAPVVHLDLAEVTRLDTAGAQLLC
RAAASMATAGARVVWHVSDHGQSMLLDRVRAIDISAVPRARRISPVVGALNAIGGSIVEE
LEQARAIIGFLGMFLVSLAAAVARPWRLRWVSIVHHMEQTGIQAVPIVALLTFLIGLVTA
YMGSEQFTRFGAQVFVVNLIEVSTLRELGVLLTALIVAGRSGSSFTAQIGAMVANEEVDA
MRSMGLDPMEVLVIPRVVALVLMLPVLTFIADFMGVLGGGIASWLSLGISPGAFAVRFQE
ITRLANFVTGLVKAPFFALIIGIVGCFQGFRVTGSAESVGRLTTQAVVESIFLVIVANAG
FAILFMSLGV