Protein Info for DvMF_1492 in Desulfovibrio vulgaris Miyazaki F

Annotation: multi-sensor hybrid histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1029 transmembrane" amino acids 41 to 66 (26 residues), see Phobius details amino acids 269 to 289 (21 residues), see Phobius details PF11845: Tll0287-like" amino acids 75 to 251 (177 residues), 64.4 bits, see alignment E=4e-21 PF00512: HisKA" amino acids 303 to 398 (96 residues), 46.4 bits, see alignment E=8.3e-16 PF02518: HATPase_c" amino acids 445 to 580 (136 residues), 74.6 bits, see alignment E=2.1e-24 PF00072: Response_reg" amino acids 650 to 763 (114 residues), 78.1 bits, see alignment E=1.5e-25 PF01627: Hpt" amino acids 894 to 969 (76 residues), 44.9 bits, see alignment 2.8e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1492)

Predicted SEED Role

"multi-sensor hybrid histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DLR4 at UniProt or InterPro

Protein Sequence (1029 amino acids)

>DvMF_1492 multi-sensor hybrid histidine kinase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MTQHQTQPPARPAGETPGALPGRAARSLRSRLRRKRPALRWNIQTFIVPAVLVAVWGVLL
LALYQWNARTEAAHVRELALLQARAFFSQIVSTRAWNAAHGGVFVRTSELGQPNPWLPPD
QRILLAADGTMLTRMNPAYMTRQISEFLTTSQGVSFRITGLHPLRQENEADPWENESLQA
FSKGARETFTLALPPDGEQPRAAERTAGSGDTRHGPSFRYMAPLMVDQSCLGCHRTADDT
VGGLRGGISVSIAATPLLALERQRLDQTALAYAIIGVVGLLGIGGASLQVSRKKALAEAA
NRMKSAFLANMSHDMRTPLTGIIGMAELLSGFQPCGAGAPSGAAAAAHAPAEASLDIDAQ
QAEHGARYNEYLGQLRCAAANLLEIVNDITDFSCLESGRMRLAPRTFRLRPSLDACLGVF
RFAGERKGLSLSLHVAENVPEALVGDDFRLRQALGNLIGNAVKFTRQGGIAVVVNLVPEQ
VPHMTPAAAADSLHRPGAGTAPREVLLRFAVVDTGVGIPAEQQESIFESFVQGEAASSLC
LGGTGLGLAISREIARMLDGDIGVSSTPGTGSEFWFTARFTLAGPPPDEDTKGDADADGD
DASAPGTGLAAWVGTSDGRGACPAPPMARETGRAAETGSAGGTSAPLRLLVADDNPVNRL
FMQDVLRGAGHQVAVATDGVQALRLLEELRPDLALLDVRMPGCDGTEVVRRLRAGLVPGV
APDMPVLAVTASAVGRESAALLGAGMTGCVCKPLTAAMLLSAVADAATGGTPLECPGTGG
YADDMHHWSDGEGPATSRTGMPPAESRGQTLPGGPAVHDRSAAPGAADGPGVPHAPGASH
LPGMSGIPGAPNATDAQDITDVTAAAAAPGASDVMDEAAALDALGGNRPLFVKLCRAFLD
EVDARRDALTAAVREGRRQDALREAHALRNSAGMLRLSALHGLCDELEQAAGRPATAPGA
QLPDMLDRLLPLLEAGVARVRIVTTQPDATGTTGPTGATSSTGSTGSTGSTGSTDTATPG
TAPVKETHR