Protein Info for DvMF_1488 in Desulfovibrio vulgaris Miyazaki F

Annotation: protein of unknown function DUF1063 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 PF03313: SDH_alpha" amino acids 183 to 438 (256 residues), 170.5 bits, see alignment E=3e-54

Best Hits

Swiss-Prot: 100% identical to Y1488_DESVM: UPF0597 protein DvMF_1488 (DvMF_1488) from Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1488)

Predicted SEED Role

"Inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DLR0 at UniProt or InterPro

Protein Sequence (446 amino acids)

>DvMF_1488 protein of unknown function DUF1063 (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MDIAAFFAAEVKPALGCTEPGAVALAAATAARHLPAPPERIHLRLSANIYKNGQSVGIPG
AQGLRGNMLASALGALAGDADMGLQALAAVTADDVAAARALTERGAVTQEIVQDVPTVYA
EAELYRPGHLVVAVVAGRHDRVAEVRHNGQVVYRAEDALGGDSLPPYMADLQRAAFGDLW
NWADGIDADLARDLLRGAEMNLAVAEQGLANPWGLAVGHTLGMALRGGDCRNDSASDARA
PGSCVPDACGPDISARVKATTAAAADVRMAGANQPVMSSAGSGNHGLTAIIPPALAARAW
GRSDAELARALALSHLVTGAVKARTGRLTPLCGCAVAAGAGAAAALVRLADGTPAQAEQA
VALVFSSVMGMICDGAKGGCALKVGTAAAEAWSAAQLALHGPGMTGAEGIVSPDFRASLR
SLGEVSSLGFAAVDVAIIRLLERGVQ