Protein Info for DvMF_1430 in Desulfovibrio vulgaris Miyazaki F

Annotation: major facilitator superfamily MFS_1 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 transmembrane" amino acids 29 to 52 (24 residues), see Phobius details amino acids 62 to 84 (23 residues), see Phobius details amino acids 96 to 114 (19 residues), see Phobius details amino acids 125 to 144 (20 residues), see Phobius details amino acids 154 to 176 (23 residues), see Phobius details amino acids 182 to 204 (23 residues), see Phobius details amino acids 216 to 236 (21 residues), see Phobius details amino acids 242 to 261 (20 residues), see Phobius details amino acids 281 to 305 (25 residues), see Phobius details amino acids 317 to 335 (19 residues), see Phobius details amino acids 347 to 366 (20 residues), see Phobius details amino acids 372 to 396 (25 residues), see Phobius details amino acids 417 to 435 (19 residues), see Phobius details amino acids 455 to 472 (18 residues), see Phobius details PF06609: TRI12" amino acids 36 to 214 (179 residues), 31.7 bits, see alignment E=1.5e-11 PF07690: MFS_1" amino acids 36 to 423 (388 residues), 206.9 bits, see alignment E=1.1e-64 amino acids 285 to 483 (199 residues), 71.8 bits, see alignment E=1.3e-23 PF05977: MFS_3" amino acids 55 to 189 (135 residues), 37.4 bits, see alignment E=2.8e-13 PF12832: MFS_1_like" amino acids 59 to 188 (130 residues), 25.7 bits, see alignment E=1.4e-09 amino acids 292 to 434 (143 residues), 26.2 bits, see alignment E=1e-09 PF00083: Sugar_tr" amino acids 62 to 201 (140 residues), 26.4 bits, see alignment E=8.2e-10

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_1430)

Predicted SEED Role

"efflux PumP antibiotic resistance protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DRU1 at UniProt or InterPro

Protein Sequence (497 amino acids)

>DvMF_1430 major facilitator superfamily MFS_1 (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSPASFPCRTPGHVASAPGQSPAPVSRGAVLFVVSTSMVLMPLMMSAVGVSLPAIGRDLA
ATAMQVGLVETTYVMALSVFLLIMGRLGDIFGRRRLFLAGLVLFTTITAVLSLSQSIRMV
IGLRFLQGMGAAMIVANSFAIMLEVFPREERGRAIGIVSAAAYAGISCGPLIGGFLTTHF
GWRWVFLMVLPFGISALLLVFTRLRGEWRSARGEPFDLRGSLVYAGTIVLLTLGSSHLDE
GAWAWGALAAGLACGGLFLWLESRTPFPLLEVTLLSRNRLFTLSCLSALINYASTFGVLF
FLGLYLQYVRGLTPSDAGLLMIIQPVIQMVLSPVGGRLADRFPAERVATVGMVLCAVGLG
VAAFIGQDTSTALTVVVLVLLGVGYGLFASPNASAIVGSVEPRHLGVASGMTSTMRTLGM
MASMIVVTIVFSVFMGGEPVSAATLPGFLSSMRTALWTFCALCAVGVLLSVGRVRSKGRG
QDSAAPDNAPCKADGTP