Protein Info for DvMF_1311 in Desulfovibrio vulgaris Miyazaki F

Annotation: selenocysteine synthase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 506 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF12390: Se-cys_synth_N" amino acids 5 to 66 (62 residues), 24.9 bits, see alignment E=1.8e-09 TIGR00474: L-seryl-tRNA(Sec) selenium transferase" amino acids 42 to 482 (441 residues), 615.4 bits, see alignment E=3.2e-189 PF03841: SelA" amino acids 104 to 469 (366 residues), 552.9 bits, see alignment E=3.6e-170

Best Hits

Swiss-Prot: 82% identical to SELA_DESVH: L-seryl-tRNA(Sec) selenium transferase (selA) from Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303)

KEGG orthology group: K01042, L-seryl-tRNA(Ser) seleniumtransferase [EC: 2.9.1.1] (inferred from 100% identity to dvm:DvMF_1311)

Predicted SEED Role

"L-seryl-tRNA(Sec) selenium transferase (EC 2.9.1.1)" in subsystem Selenocysteine metabolism (EC 2.9.1.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.9.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DLJ8 at UniProt or InterPro

Protein Sequence (506 amino acids)

>DvMF_1311 selenocysteine synthase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSNLFRSLPSMDALLTALAHPEQAGPGTPAASEQAARSAQSARADLAALPRPLLRDLVNA
FLDRCREAIRAGTITDAAALSTQALLPALMAHVLRAARPHFRRVLNATGVVIHTNLGRSL
LAEEATAAVAEACANYSNLEFDLSTGERGSRYSHVEELLCKVTGAEAGLVVNNNAAAVLL
VLDTLCKGGEVVVSRGQLVEIGGSFRIPEVMEKSGAVLREVGATNRTHLRDYENAINERT
VALLKVHTSNYRITGFHKEVPLAELVALGRARNLPVIEDLGSGSFLDFTPWGLHGEPTVR
EVVADGADVVSFSGDKVLGGPQAGLIVGRREIIARIKRNPLNRALRIDKMTLAALEATLR
LYLDPELARRKVPTLRMMTAPADELARRARRLATRLRTALGDAATIGLAPGVSRVGGGSF
PERDLPTTLVSVAPAGCSATALKERLLDTDPPLVGRLEDDTFRLDPRTLNDTEFPLAAAA
LAQALGLPDTPNAARPGKRASRARRG