Protein Info for DvMF_0696 in Desulfovibrio vulgaris Miyazaki F

Annotation: secretion protein HlyD family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF16576: HlyD_D23" amino acids 64 to 307 (244 residues), 42.4 bits, see alignment E=1e-14 PF13533: Biotin_lipoyl_2" amino acids 67 to 107 (41 residues), 32.2 bits, see alignment 1.5e-11 PF13437: HlyD_3" amino acids 224 to 307 (84 residues), 33.9 bits, see alignment E=9.1e-12

Best Hits

KEGG orthology group: K02005, HlyD family secretion protein (inferred from 100% identity to dvm:DvMF_0696)

Predicted SEED Role

"secretion protein HlyD family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DK57 at UniProt or InterPro

Protein Sequence (353 amino acids)

>DvMF_0696 secretion protein HlyD family protein (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MKPRLVVFAALVGVASVLAFSRSVQPPLNGLMPRTSAAAALEERKQGWIVASGRVEPVTK
ELVLGFETSGVIETLHVAEGDKVEQGQLLARLRNEVELAQLDEARANALAARMELEKLTN
GARPEEKGEAQARERRALKVFEQARQEAARRQRLRFQDAISREDMERAQRDMDVAKQEYD
AAWQQLKLVEDMYRREDVAKAGHQLAAAEAAVRVAESTLRRMDLRSPVAGTVLRVFGEAG
EVFSLFAPSPVISVGDIAALNVRTEVDERDIGRVRVGQAAYVRADAYGSERFGGKISRVV
LSLTPKTLRTGNPSEPVDRSVLEVLITLDAPGPLVSGLRVDAYIDASALPLPQ