Protein Info for DvMF_0661 in Desulfovibrio vulgaris Miyazaki F

Annotation: integral membrane sensor signal transduction histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 57 to 81 (25 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 166 to 186 (21 residues), see Phobius details amino acids 197 to 215 (19 residues), see Phobius details amino acids 230 to 250 (21 residues), see Phobius details amino acids 265 to 283 (19 residues), see Phobius details amino acids 325 to 346 (22 residues), see Phobius details PF02518: HATPase_c" amino acids 572 to 674 (103 residues), 70.2 bits, see alignment E=9.9e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_0661)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DK22 at UniProt or InterPro

Protein Sequence (686 amino acids)

>DvMF_0661 integral membrane sensor signal transduction histidine kinase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MVIALAGIALVLAVVITGRAFCEPGRVALCRVPAPLVTAALVASESHLAVATDLPDWLLP
LVLLLQALLAPAWTVFALCYGRECSWRMLPRSGKFLLALALSPLFMILFTSPGDMFYLAD
FTAERVLYLEPHAFFFYVQLLLCLLLSAGILESTLRSSRHSERWRIKLALVGAGVVLAAL
CLQYGQGLVVRTLDFGYTGLRNSAVVLGFGLFLYAEARRGSDKVYITRRLAFRSIVAVIA
GGYLLGLGVLREGMRLMGPGFERHFALAIAFVISLAVLLTLLSDHLRRRFSIWMHRTFYN
EKYDYRTQWINFTDMLSHARGTKEFINVLLVGLCDAFGFVGGAFIPADLEHPGGMRDGVL
YEMEPLPVLPATSFAALFEREGGPCPVGDVAESVPAEAFEALCSAGVSVVLPVRTVEGSE
GIVLLARPIDTHEEHDIEDFELLEAMGRQIALCVRSFRLGDELAVAREMEVLGRFAALVM
HDLKNQVYALSLLVDNAREYIGEPDFQRDLVETLTNSVANMRNLISQLTRLPGRESLQME
EVDLMELARSACGQLPNADIQFMGTGVRVRVDAEQVAKVFVNLCLNAIEAGGNKRVAVHV
GDDGRPFFHVVDSAGGIDPALLRDGLFKPFRTTKARGMGIGLYHCRKIIEAHGGTISAES
HPGKGTTFTVRFEAAAVGEAAPDAKA