Protein Info for DvMF_0610 in Desulfovibrio vulgaris Miyazaki F

Annotation: indolepyruvate ferredoxin oxidoreductase, alpha subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 629 TIGR03336: indolepyruvate ferredoxin oxidoreductase, alpha subunit" amino acids 28 to 618 (591 residues), 710.6 bits, see alignment E=7.1e-218 PF01855: POR_N" amino acids 40 to 215 (176 residues), 43.5 bits, see alignment E=3.3e-15 PF02775: TPP_enzyme_C" amino acids 411 to 552 (142 residues), 74 bits, see alignment E=1.2e-24

Best Hits

KEGG orthology group: K00179, indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC: 1.2.7.8] (inferred from 100% identity to dvm:DvMF_0610)

Predicted SEED Role

"Indolepyruvate oxidoreductase subunit IorA (EC 1.2.7.8)" in subsystem Aromatic amino acid interconversions with aryl acids (EC 1.2.7.8)

Isozymes

Compare fitness of predicted isozymes for: 1.2.7.8

Use Curated BLAST to search for 1.2.7.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DJX1 at UniProt or InterPro

Protein Sequence (629 amino acids)

>DvMF_0610 indolepyruvate ferredoxin oxidoreductase, alpha subunit (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MSESTATSGATPGARPVNPLLADEPGARRLLLGNEAIVRGALEAGVNLVACYPGTPSSEV
PDTFRRIGGGGRYRLEYSVNEKVAMEVGAGAALAGALTLVTMKHVGVNVAADPLLTMTYT
GLPGGLLLLSADDPGCHASQNEQDNRTYARFAGMPCFEPATAQEAKDMTRDALLLARELE
QPVLLRTTTRVNHLRGAVEFGPLGQPAPIVPFERNPRRFVPVPAVARVRHAELVKHLGMA
REKAEHSPWNTVRGEGRFGVIASGISRAYLSDALHETGWDDRVKVLDLGMTWPLPEALLT
DFLSQCDAVLVLEELEPLLENDVRALVQRNNLPVAVSGKGGALTIYGEYSTQTVTQALAD
LLGETARLPIACDPETALPVRPPNLCPGCSHRALYYAVRKVFGDDAVYSSDIGCYTLGLL
PPLRMADFLFCMGSSVSSGSGFATASGKPTLAFIGDSTFFHSGITGLVNAVFNKHDLIVV
VLDNGTTAMTGHQPNPGVVQEVLGNACVHLDIEAVVRGCGVADVVKVRPFNVKSTMKALA
EMKERSGVRVIIAEEPCVLYARRTLKKPRNQVAYVAEQGPSVADCLEHLACPAFFRDDTG
IHVDENLCGGCMVCLQVADTIKARKRSDA