Protein Info for DvMF_0590 in Desulfovibrio vulgaris Miyazaki F

Annotation: ATP-dependent protease, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 811 PF20437: LonC_helical" amino acids 92 to 123 (32 residues), 44.6 bits, see alignment (E = 2.4e-15) PF13654: AAA_32" amino acids 329 to 459 (131 residues), 152.5 bits, see alignment E=1.4e-48 PF20436: LonB_AAA-LID" amino acids 488 to 552 (65 residues), 66.1 bits, see alignment E=4.8e-22 PF05362: Lon_C" amino acids 662 to 765 (104 residues), 31.5 bits, see alignment E=2.6e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_0590)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type II" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DKW8 at UniProt or InterPro

Protein Sequence (811 amino acids)

>DvMF_0590 ATP-dependent protease, putative (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MTKVSPLPAARLRATLDPTRIRWETSDAIPRPPRNGMRRTPQPRVLQALELALHIRDGGY
NVYLSGEANLGRTYMLREYLAPRARKMDTPPDLIHVYNFEDPDRPRLIALPAGQGRKLRT
ALTQALSKARKEAPSRFEHDAFVRKRTLLLDKFQTQRSKLFKEMDTVAGGEGFNLDMDDS
GSLTLYPIVEGKRLSEDEYEKLDATLRKSLKLKGDRLLQAMTGLMRKLTRAEQDFVEDER
TLEKEVVREVLDQFLTPLADKFAKTCPCDELKRYFADMREDILDNIEGFVQRDMPTHMPQ
QQPDLGPPPEDTSFRYDINVFVDNSETHGAPIVVDDHPTPSNLLGCIERESEMGALVTDF
TLVKAGSLQKANGGFLVLHMEDILSYPSAWEGLLRALRSGLARIEDAGDGQESTKTKGIE
PEPLRLNLKVVLVGTEEMYETLLVNDDRFPKLFKIKAHLTEATERNADGVKVYLARIARI
IDESKLLPFDRDAMAGLVDYGSRIIEDQRKLSLKFPVLRELMIEASALASMKGSALVDRT
TLHDAMVARTYRANLVEQHYMDEYDRELIKVRTSGSEVGRVNGLSVTWYGDFEFGLPHQI
SCTVGVGHGGIIDLEREAELGGPIHTKAMMILKSYLVSQFARTKPLVMTGSLCFEQSYAG
IEGDSASGAELAALLSAIADVPIRLSLAFTGAVSQSGQIMAVGGVTRKVEGFFEVCSRHG
LTGEQGVILPKDNIAHLMLKQEVVAAVNEGRFSIWPVAHITEAMELLTGMPAGRMRADST
FSPGTLYDKVDRRLAELGRLAKDAFKQKRKR