Protein Info for DvMF_0493 in Desulfovibrio vulgaris Miyazaki F

Annotation: diguanylate cyclase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 356 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 167 to 351 (185 residues), 118 bits, see alignment E=1.8e-38 PF00990: GGDEF" amino acids 169 to 348 (180 residues), 111.4 bits, see alignment E=1.9e-36

Best Hits

KEGG orthology group: None (inferred from 100% identity to dvm:DvMF_0493)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DKM1 at UniProt or InterPro

Protein Sequence (356 amino acids)

>DvMF_0493 diguanylate cyclase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MADNTCNCSRRQCTFSGGERLCEILDRAGVPHDSKWRTLVFYMRGLGEFSTMNDDQKARI
QQLLVDVLHRRDFSEQSYHEVLRADRDIRVEPYECRMREALQETERLAREFRVMLHQRRG
DMDKLEQDSVRAVESGLDPAEVVRLLRATFSEVREQMDNDAIRVGELTVTDPLTGLGNRR
AFDTALTAGEAAWKGGTALALVLFDVDRFKRINDQHGHRIGDQVLRTVAEVLRRKVDDCN
RSLNDEAEGAGECASVVARFGGEEFALVLTGEGAQRAGEIAESVRAGLESVNFAIRDGQG
HVVEHGVRVTLSAGVAHARPGMPEPLTDALFDLADKALYEAKREGRNRVRVVAGPI