Protein Info for DvMF_0022 in Desulfovibrio vulgaris Miyazaki F

Annotation: metal dependent phosphohydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 361 PF01336: tRNA_anti-codon" amino acids 31 to 91 (61 residues), 30.1 bits, see alignment E=3.7e-11 TIGR00277: HDIG domain" amino acids 164 to 230 (67 residues), 32.1 bits, see alignment E=4.1e-12 PF01966: HD" amino acids 167 to 284 (118 residues), 61.7 bits, see alignment E=7.9e-21

Best Hits

KEGG orthology group: K03698, CMP-binding protein (inferred from 100% identity to dvm:DvMF_0022)

Predicted SEED Role

"3'->5' exoribonuclease Bsu YhaM"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See B8DN40 at UniProt or InterPro

Protein Sequence (361 amino acids)

>DvMF_0022 metal dependent phosphohydrolase (RefSeq) (Desulfovibrio vulgaris Miyazaki F)
MEKRQTIRDIAANDEVSGLFLLGSATLQQSRNGPFWRLELRDATGSMEAKIWSPQSQAYP
DLAAGQIVDVEGRSGTYRDKVEVTIGRLRVLDDVEQAGLDLGLFLPASPRPAQEMLDELI
ALCKAEFTHAPWRKFVLAVLRDEDIAPRLLAAPAAKSVHHAYVGGLVEHMLSVAGLALRI
ADHYPELDRQALLAGALFHDIGKVWELTGGLANDYSDEGRLLGHIHIGLERIEPHLRKSG
LAPELVTHFKHLILSHHGEYEFGSPRRPKTAEAMALHYADNLDAKMAQFRGLFANHEEDA
TGWTPFQPTLGRFLYRPARSPEEPRPARKSSPAHKGGGKAGADGADDAAKAGPQSVQASL
L