Protein Info for Shewana3_4108 in Shewanella sp. ANA-3

Annotation: isoprenoid biosynthesis protein with amidotransferase-like domain (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 signal peptide" amino acids 1 to 17 (17 residues), see Phobius details PF01965: DJ-1_PfpI" amino acids 13 to 141 (129 residues), 26.9 bits, see alignment E=2e-10

Best Hits

Swiss-Prot: 44% identical to GAL3A_MOUSE: Glutamine amidotransferase-like class 1 domain-containing protein 3A, mitochondrial (Gatd3a) from Mus musculus

KEGG orthology group: None (inferred from 100% identity to shm:Shewmr7_3996)

Predicted SEED Role

"Sigma cross-reacting protein 27A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L2Q6 at UniProt or InterPro

Protein Sequence (218 amino acids)

>Shewana3_4108 isoprenoid biosynthesis protein with amidotransferase-like domain (RefSeq) (Shewanella sp. ANA-3)
MKKIAVLLSGCGVFDGTEIHESVLTLLSLSKAGAQYQCFAPDINQMHVVNHFTGEVDKTA
TRNVLVESARIARGEVKATTELDITDFDALVIPGGFGAAKNLCNFATNGSECEVNPLVTD
FINEFILAKKPVGFICIAPMMIPRLYGHGAKGTIGNDVDTVAAFNLMGGHHQAATVHDIV
VDEANKIVSTPAYMLAGNIAEAHSGIEKLVAKVLELAK