Protein Info for Shewana3_4080 in Shewanella sp. ANA-3

Annotation: molybdenum cofactor guanylyltransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 197 TIGR02665: molybdenum cofactor guanylyltransferase" amino acids 5 to 187 (183 residues), 253.3 bits, see alignment E=8e-80 PF12804: NTP_transf_3" amino acids 7 to 157 (151 residues), 142.8 bits, see alignment E=5.5e-46

Best Hits

Swiss-Prot: 100% identical to MOBA_SHESA: Molybdenum cofactor guanylyltransferase (mobA) from Shewanella sp. (strain ANA-3)

KEGG orthology group: K03752, molybdopterin-guanine dinucleotide biosynthesis protein A (inferred from 99% identity to she:Shewmr4_3877)

Predicted SEED Role

"Molybdopterin-guanine dinucleotide biosynthesis protein MobA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L2M8 at UniProt or InterPro

Protein Sequence (197 amino acids)

>Shewana3_4080 molybdenum cofactor guanylyltransferase (RefSeq) (Shewanella sp. ANA-3)
MSLQIDAVILAGGMARRMGGDDKGLVELNGKAMIEHTIERIKPQVKEILINANRNQTRYA
EFGFTVLSDEHTGFLGPLAGTITAMGHTQADYLLVVPCDCPLLPRDLVARLLAAIEANDA
ELAVASDGEREQPVVMLLKPSLRESMTAFLEAGERKIDFWYAKHRFAVAAFADQPNAFVN
VNTPEQKQRLAAEINQS