Protein Info for Shewana3_4016 in Shewanella sp. ANA-3

Annotation: putative PAS/PAC sensor protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1626 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 225 to 243 (19 residues), see Phobius details amino acids 312 to 333 (22 residues), see Phobius details PF03924: CHASE" amino acids 79 to 264 (186 residues), 166.9 bits, see alignment E=2.1e-52 TIGR00229: PAS domain S-box protein" amino acids 344 to 467 (124 residues), 69.4 bits, see alignment 1.5e-23 amino acids 497 to 611 (115 residues), 55 bits, see alignment 4.4e-19 amino acids 629 to 756 (128 residues), 45.6 bits, see alignment E=3.5e-16 amino acids 804 to 885 (82 residues), 24.8 bits, see alignment 9.8e-10 PF00989: PAS" amino acids 347 to 458 (112 residues), 46.8 bits, see alignment 1.2e-15 amino acids 507 to 604 (98 residues), 36.6 bits, see alignment 1.8e-12 amino acids 632 to 746 (115 residues), 35 bits, see alignment 5.8e-12 PF13188: PAS_8" amino acids 350 to 386 (37 residues), 21.6 bits, see alignment (E = 7.2e-08) PF08448: PAS_4" amino acids 352 to 462 (111 residues), 50.3 bits, see alignment 1.2e-16 amino acids 508 to 608 (101 residues), 36.2 bits, see alignment 2.8e-12 amino acids 626 to 748 (123 residues), 28.7 bits, see alignment 5.8e-10 PF13426: PAS_9" amino acids 357 to 460 (104 residues), 37.3 bits, see alignment 1.3e-12 amino acids 508 to 606 (99 residues), 46.5 bits, see alignment 1.7e-15 amino acids 631 to 748 (118 residues), 43.2 bits, see alignment 1.9e-14 PF08447: PAS_3" amino acids 516 to 598 (83 residues), 43.8 bits, see alignment 1.1e-14 amino acids 784 to 873 (90 residues), 60.8 bits, see alignment 5.7e-20 PF00512: HisKA" amino acids 899 to 964 (66 residues), 67 bits, see alignment (E = 5.5e-22) PF02518: HATPase_c" amino acids 1012 to 1124 (113 residues), 99 bits, see alignment 1e-31 PF00072: Response_reg" amino acids 1143 to 1262 (120 residues), 70.3 bits, see alignment 7.1e-23 amino acids 1289 to 1398 (110 residues), 87.8 bits, see alignment 2.6e-28

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_4016)

Predicted SEED Role

"Probable sensor/response regulator hybrid (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L2G4 at UniProt or InterPro

Protein Sequence (1626 amino acids)

>Shewana3_4016 putative PAS/PAC sensor protein (RefSeq) (Shewanella sp. ANA-3)
MTLSMSYKQASKWGLFVLLVGLFFSAVLAWQVSRINAQTISQALEERAQQISENVTNRIT
LYQYGLRGARGMILTAGEDHISRSMFQNYSLTRDVDEEFPGARGFGFIRRVPKENEAQFL
ARVKSMDWPDFHIRQLNPNEGEKYLIEYIEPLDRNKAAVGLDIASESHRKEAADRALLSG
AVQISAPITLVQATGKPLQSFLILLPVYRSGTVPKTPEERLAQGFGWSYAPLVTTEILTG
LSLHQKMTKLMLSDVTDEQQPINFFETHANDLSELSDYSYKSTKTIFGRHWQFEVIAYPA
FIKSLHLNKPSLVLFSGCLFSLLLAALIAMWSLSLQRKQQVLAEQARRASMLEHSLDGII
SYDLAGNITSWNQGAERLFGFTEPETLGLPSSELIVPPSIVLEEQALFAEVLAGKTVLNR
VSRHQRADGSNLSTSTTALPIYDEHGDIVGLSQTIRDITAQQDAERHILNLNASLERQVA
KRTHALQQALLENQALLDTINQQLHYSVTDLDGVILDVNEHFCLISGYAREELVGKTHAV
LKSGEHDAAFWKAMWEQIKAGKSWHGEICNRGKDQQLKWFDTVIGSVFDEHGQVERFVAL
QTDITERKLAQIEKNRIATLLTNVLDAASEMTIIAADPQGIITIFNRGAERMLWYSAEEI
IGKTTPAPFHIADEIAARAAELSVEYGQKIQGFDTFVHKAREEGSETRTWTYVRKDGSQL
PISLSVTAMRGNDGEILGYLGIGVDISQIVAQQEALLTASNHLSKAAEVAKLGIWTWNLL
DNSLQWNDRMFAMYDQPESLKQQGLSYEHWRMRVHPDDVIEAEETLKRAVEHDEPYEPIF
RILTTDGEVRYVQAAAKIERDRQGHVIRVIGINIDITAQRQLEKTLRNAKQEADTANAAK
SAFLANMSHEIRTPMNAVLGMLQLMQYTALSVQQQGYVTKAQTAAKSLLGLLNDILDFSK
IDAGKLKLDLHPCSIELLMRDLAVVLSANHGNSDVEVMFDLDSALPAWLLADQLRLQQIL
INLAGNALKFTPHGQVIVGLECLRHEAESVTVQFSIVDSGIGISEEQIERIFTGFEQAES
STSRRFGGTGLGLAISKRLVELMGGQLQVTSKVGVGSRFWFDLTFPVMEVEANPRADLSG
YRILVVDDNQITTEILSKILSDYGCVVETASGGYQAIEKVKQATANAQQFDVVLMDWRMP
DIDGLQTAEMLKNAGTGSYTPLVVMLTAYGHEVIAESQHINNVPFVNFLTKPVTSQILAE
AVLNAIEGKTMDANPKPRSQRLLAGLTLLVVEDNQLNREVIDELLTYEGATVVLAEGGIE
GVTQVLDSGDMFDAVIMDMQMPDIDGLEATRRIRADGRFDQLPILAMTANASQADKQECL
EAGMNAHVSKPIDMQQLLPNILRLVGRDAAQFAEPESMHLDAQHNLEGETLLDDIRLILR
RFGGNQVFFEKMASSFAPEMIKQLSLFKQSTKTFDYATTAAISHAIKGIASNFGARRLAV
HAAFLEKQFKQEGLELLEIKRWTDTLESLINQSIEQLSGFLPKTQLKQSQSSESANGVVD
IQSVRAELDNLASLLQENNLEAVTLVDKLAKPLSQHPQWTELNGQVQSLAFMQALETLRA
MMLENA