Protein Info for Shewana3_4014 in Shewanella sp. ANA-3

Annotation: transcription elongation factor GreB (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 167 TIGR01461: transcription elongation factor GreB" amino acids 3 to 156 (154 residues), 229.7 bits, see alignment E=6.7e-73 PF03449: GreA_GreB_N" amino acids 5 to 74 (70 residues), 74.8 bits, see alignment E=5.2e-25 PF01272: GreA_GreB" amino acids 81 to 155 (75 residues), 80.2 bits, see alignment E=8.7e-27

Best Hits

Swiss-Prot: 69% identical to GREB_VIBVY: Transcription elongation factor GreB (greB) from Vibrio vulnificus (strain YJ016)

KEGG orthology group: K04760, transcription elongation factor GreB (inferred from 100% identity to shn:Shewana3_4014)

Predicted SEED Role

"Transcription elongation factor GreB" in subsystem Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L2G2 at UniProt or InterPro

Protein Sequence (167 amino acids)

>Shewana3_4014 transcription elongation factor GreB (RefSeq) (Shewanella sp. ANA-3)
MKAHLITRQGWMTLDKELKYLWKEYRPQITLKVQEAAAQGDRSENADYTYNKRLLRQIDS
RVRYLVKRLEELKIVDYSPQQEGKIYFGAWFELENEAGECVRYRIVGKDELDTKLGYITI
DSPMARALIGKQVDDEVVVQTPSGPKEWYINDIRYTPFETPLEGEPE