Protein Info for Shewana3_3690 in Shewanella sp. ANA-3

Annotation: cytochrome c, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR04315: octaheme c-type cytochrome, tetrathionate reductase family
  • amino acids 22 to 446 (425 residues), 636 bits, E=1.8e-195
• PF13435: Cytochrome_C554
  • amino acids 39 to 120 (82 residues), 18.5 bits, E=8.3e-07
• PF11783: Cytochrome_cB
  • amino acids 265 to 435 (171 residues), 227.7 bits, E=2.1e-71

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_3690)

MetaCyc: 97% identical to tetrathionate reductase (Shewanella oneidensis MR-1)
HAONITRO-RXN [EC: 1.7.2.6]; Nitrite reductase (cytochrome; ammonia-forming). [EC: 1.7.2.6, 1.7.2.2]; 1.21.99.M4 [EC: 1.7.2.6, 1.7.2.2, 1.21.99.M4]

Predicted SEED Role

"Octaheme tetrathionate reductase" in subsystem Tetrathionate respiration

MetaCyc Pathways

• nitrate reduction IV (dissimilatory) (2/2 steps found)
• tetrathionate reduction I (to thiosulfate) (1/1 steps found)
• formate to nitrite electron transfer (2/3 steps found)
• ammonia oxidation I (aerobic) (1/2 steps found)
• superpathway of tetrathionate reduction (Salmonella typhimurium) (2/4 steps found)
• nitrifier denitrification (2/6 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.7.2.2

Use Curated BLAST to search for 1.21.99.M4 or 1.7.2.2 or 1.7.2.6

Sequence Analysis Tools

See A0L1J0 at UniProt or InterPro

Protein Sequence (462 amino acids)

>Shewana3_3690 cytochrome c, putative (RefSeq) (Shewanella sp. ANA-3)
MKKLIVIALAGMALQAQAANPHKDVLKGPFATGSEVTTQCLTCHEEQATDMMKTSHWTWE
LEQKLPDRTVLRGKKNSINNFCVSISSNEPRCTSCHAGYGWKDSNFDFKDKTKVDCLVCH
DTTGTYVKDPAGAGEPMAKLDLAKIAQNVGEPVRDNCGSCHFYGGGGDAVKHGDLDSSMA
YPDKATDVHMDSDGNNFQCQNCHTTEKHQISGNAMGVSPGGIDHIGCENCHDSAPHSNKK
LNTHTATVACQTCHIPFFAKNEPTKMHWDWSTAGDDKPETVDQYGKHTYQKKKGDFVWEK
MVKPQYAWYNGTANAYMAGDKMDPNVVTKLTYPMGDINDAKAKIYPFKVHTGKQIYDKKL
NIFITPKTYGKGGYWSEFDWNLAAKLGMEANPTMLEKGIKYSGEYDFAATEMWWRINHMV
SPKEQALNCNDCHNKGTRLDWQALGYQGDPMKNKQGPKHKQP