Protein Info for Shewana3_3595 in Shewanella sp. ANA-3

Annotation: DEAD/DEAH box helicase domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 619 PF00270: DEAD" amino acids 30 to 195 (166 residues), 167 bits, see alignment E=6.6e-53 PF04851: ResIII" amino acids 45 to 189 (145 residues), 30.7 bits, see alignment E=5.9e-11 PF00271: Helicase_C" amino acids 231 to 339 (109 residues), 108.5 bits, see alignment E=4.5e-35 PF03880: DbpA" amino acids 487 to 557 (71 residues), 77.9 bits, see alignment E=9.6e-26

Best Hits

KEGG orthology group: K05592, ATP-dependent RNA helicase DeaD [EC: 3.6.4.13] (inferred from 100% identity to shn:Shewana3_3595)

Predicted SEED Role

"DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)" (EC 3.6.4.13)

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L198 at UniProt or InterPro

Protein Sequence (619 amino acids)

>Shewana3_3595 DEAD/DEAH box helicase domain-containing protein (RefSeq) (Shewanella sp. ANA-3)
MSSSERTFRELGLSENLLRALDELGYENPTPIQSASIDPLMAGKDILGQAQTGTGKTGAF
ALPLLNKVTSQAVPQILVLAPTRELAVQVAEAFSSYAKFMKGFHVLPIYGGQSMHQQLNA
LKRGPQVIVGTPGRVMDHMRRGTLKLETLQALVLDEADEMLKMGFIDDIEWILEHTPEQR
QLALFSATMPEQIKRVANKHLKDATNISIAASHTTVDSIEQRFVQVSQHNKLEALVRVLE
VENTEGIIIFVRTRNSCVELAEKLEARGYASSPLHGDMNQQARERAVEQLKSGKLDILIA
TDVAARGLDVERIGHVVNYDIPYDTEAYVHRIGRTGRAGRTGMAILFVTSREMRMLRTIE
RATNSRISPMKVPSPETVAERRLSRLGEQLAQTMTQDLDFMREAVAQLCQQLEVDTDLLA
AALLHQVQQERPLQLPAIQERTRDERSERGAERGERGERRSRESRPMPASLGSAEALKDN
PDLKMCRYVIDVGRDNGVGVGNIVGAIANEANIDSRYIGAIQLYDAVTTVDLPDGMPKEV
LQHLKKVRVCGKPLNIREAGDQVFVDSGRGARSDRRPRGDRPMGERKPRSASGDKPFADR
KPRSDKPAGERRPRKPREE