Protein Info for Shewana3_3581 in Shewanella sp. ANA-3

Annotation: response regulator receiver protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 TIGR02824: putative NAD(P)H quinone oxidoreductase, PIG3 family" amino acids 9 to 331 (323 residues), 469 bits, see alignment E=3.6e-145 PF08240: ADH_N" amino acids 34 to 117 (84 residues), 57.8 bits, see alignment E=1.8e-19 PF00107: ADH_zinc_N" amino acids 158 to 273 (116 residues), 94.8 bits, see alignment E=6.3e-31 PF13602: ADH_zinc_N_2" amino acids 190 to 330 (141 residues), 81.1 bits, see alignment E=2.2e-26

Best Hits

KEGG orthology group: K00344, NADPH2:quinone reductase [EC: 1.6.5.5] (inferred from 100% identity to shn:Shewana3_3581)

Predicted SEED Role

"Alcohol dehydrogenase, zinc-containing" in subsystem D-Galacturonate and D-Glucuronate Utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.6.5.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L184 at UniProt or InterPro

Protein Sequence (332 amino acids)

>Shewana3_3581 response regulator receiver protein (RefSeq) (Shewanella sp. ANA-3)
MSELPHDYTHIYLEQPGEPEVMQLTRSPLPVPSAGQVLIRNRAAGVNGPDIKQRMGVYPP
PPGASPIIGLEVAGEICALGEGVTQWQLGDKVCALVPGGGYGEYSLTYAEHCLPIPKGFS
EVQAAALPETFFTVWGNLFMRAGLKAGETVLVHGGSGGIGSTAISLAKHLGATVIATTGQ
DAKRDYCAGLGAHLVVNYNTQNFVEEVMAFTQGKGVNVVFDIAGGDFINLNLQALALDGR
MVSVSTQRSGKAEVSILQLMAKRIVWTGSTLRPQSVAAKAEIAKQLRERVWPLLDSQQIV
PHICATFPLAEAAKAHALMQSGEHRGKVVLTL