Protein Info for Shewana3_3465 in Shewanella sp. ANA-3

Annotation: agmatine deiminase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03380: agmatine deiminase
  • amino acids 13 to 367 (355 residues), 579.4 bits, E=1.2e-178
• PF04371: PAD_porph
  • amino acids 21 to 367 (347 residues), 406.6 bits, E=4.1e-126

Best Hits

Swiss-Prot: 100% identical to AGUA_SHESA: Putative agmatine deiminase (aguA) from Shewanella sp. (strain ANA-3)

KEGG orthology group: K10536, agmatine deiminase [EC: 3.5.3.12] (inferred from 100% identity to shn:Shewana3_3465)

MetaCyc: 53% identical to agmatine iminohydrolase (Arabidopsis thaliana col)
Agmatine deiminase. [EC: 3.5.3.12]

Predicted SEED Role

"Agmatine deiminase (EC 3.5.3.12)" in subsystem Arginine and Ornithine Degradation or Polyamine Metabolism (EC 3.5.3.12)

MetaCyc Pathways

• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (3/3 steps found)
• putrescine biosynthesis II (3/3 steps found)
• superpathway of polyamine biosynthesis II (6/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.12

Sequence Analysis Tools

See A0L0W9 at UniProt or InterPro

Protein Sequence (370 amino acids)

>Shewana3_3465 agmatine deiminase (RefSeq) (Shewanella sp. ANA-3)
MTNANVDATQLTTKPSEDGFYMPAEWAAQQAVWMIWPYRPDNWRSAGAYAQATFAKVADA
IGGATPVYMGVPQAFLAEAQTVMPSHVTLVEIDSNDCWARDTGPTVVVNAEGECRGVDWG
FNAWGGHNGGLYFPWDKDEQVAAQMLKQHGFARYSAPLILEGGSIHVDGEGTCMTTAECL
LNANRNPDLTKEQIEALLRDYLNVKQFIWLEEGVYMDETDGHIDNMCCFARPGEVILHWT
DDETDPQYPRSKAALDVLQNTVDAQGRKLKIHLLPQPGPLYCTEEESKGVTEGTGVPRTA
GERLAGSYVNFLITNDRIVFPLLDPATDDIAAQKLQEIFPEHKIVGVPAREILLGGGNIH
CITQQIPSGK