Protein Info for Shewana3_3454 in Shewanella sp. ANA-3

Annotation: outer membrane efflux protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 477 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 27 to 467 (441 residues), 273.9 bits, see alignment E=1.3e-85 PF02321: OEP" amino acids 77 to 260 (184 residues), 81.7 bits, see alignment E=3.1e-27 amino acids 292 to 466 (175 residues), 69.6 bits, see alignment E=1.6e-23

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_3454)

Predicted SEED Role

"RND efflux system, outer membrane lipoprotein CmeC" in subsystem Multidrug Resistance Efflux Pumps or Multidrug efflux pump in Campylobacter jejuni (CmeABC operon)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L0V8 at UniProt or InterPro

Protein Sequence (477 amino acids)

>Shewana3_3454 outer membrane efflux protein (RefSeq) (Shewanella sp. ANA-3)
MNNRVLTHQNEVSRRVGSTLKVSVIAISIALLSGCGALMRSDFEPPALQVPEQWQHTQVN
GQVSLDPWWQKFNQPELNQLISQVLSSNNDLTLATLTLQKARLQAGLARDDLYPQLSSNN
TASVNKPLDGGSSSRAFQANLSVSYEVDLWGKVSANIDQAQWTALASLEDRESTAQSLVA
TTASLYWQIGYLHERIELSNKSIEHSRQTLALTQRQYASGAVTELNVLESQRSLAGQEAS
HSQLLQQLVEAENALAILLNRAPEQVAVEIKQLPDSAVPEVGVGIPADLVGRRPDVKAAL
YQLRSALASKDATYASYFPSLSLTGSVGESTSELKELLRNPVGSLGAGLVLPFLQWNQMQ
INNDIADIDYQSAIVSYRKTLYSAFEDVDNAISAKQQYAYQGEKLELQFSAAAQAEAIYE
SQYRHGAIGIQNWIDAQENRRSAEAALLENRYNQLTAQATLYQALGGSDIAPPLADN