Protein Info for Shewana3_3420 in Shewanella sp. ANA-3

Annotation: amino acid carrier protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 61 to 85 (25 residues), see Phobius details amino acids 92 to 110 (19 residues), see Phobius details amino acids 146 to 166 (21 residues), see Phobius details amino acids 179 to 198 (20 residues), see Phobius details amino acids 209 to 229 (21 residues), see Phobius details amino acids 243 to 262 (20 residues), see Phobius details amino acids 304 to 325 (22 residues), see Phobius details amino acids 346 to 368 (23 residues), see Phobius details amino acids 389 to 409 (21 residues), see Phobius details amino acids 415 to 433 (19 residues), see Phobius details TIGR00835: amino acid carrier protein" amino acids 15 to 438 (424 residues), 504.9 bits, see alignment E=8.6e-156 PF01235: Na_Ala_symp" amino acids 52 to 442 (391 residues), 464.2 bits, see alignment E=2.3e-143

Best Hits

Swiss-Prot: 61% identical to Y883_HAEIN: Uncharacterized transporter HI_0883 (HI_0883) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K03310, alanine or glycine:cation symporter, AGCS family (inferred from 100% identity to shn:Shewana3_3420)

Predicted SEED Role

"Sodium/glycine symporter GlyP" in subsystem Glycine cleavage system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L0S4 at UniProt or InterPro

Protein Sequence (452 amino acids)

>Shewana3_3420 amino acid carrier protein (RefSeq) (Shewanella sp. ANA-3)
MSFQALLSSLNGIVWGPVTLCLLVGTGIYLTLRLRLIQVFRLPMALGLLFKPAKGHGDLS
SFAALCTALSATIGTGNIVGVATAIKMGGPGALFWMWLAAFFGMATKYAECMLAVKYRTT
DARGQIAGGPMYYIERGLGLHWMAKLFALFGVGVAFFGIGTFAQVNAISDALTIAFEVPT
WATALVLTLLVAAVTLGGVKRISNVAQKLVPAMSIGYVLACVWILVSFAESILPALQLVV
ESAFTPVSAAGGFLGATVAQAIQMGIARGVFSNESGLGSAPIAAAAAKTNEPVEQGLVSM
TGTFFDTIIICTITGLVLIITGVWSGDTAGAAMTSAAFSLGGSAAIGQYLVTIALVCFAF
TTILGWHYYGERCWYYLVGERGLRAYQMLFLGLIAVGAFIKLDVIWLLADTVNGLMAIPN
LIAIIGLRHVIIAETQSYFVRTLSNRTLDPIY