Protein Info for Shewana3_3419 in Shewanella sp. ANA-3

Annotation: multi-sensor hybrid histidine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1767 transmembrane" amino acids 13 to 35 (23 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details PF22673: MCP-like_PDC_1" amino acids 92 to 208 (117 residues), 134.6 bits, see alignment 1e-42 TIGR00229: PAS domain S-box protein" amino acids 405 to 507 (103 residues), 24.4 bits, see alignment 1.3e-09 amino acids 515 to 636 (122 residues), 57.7 bits, see alignment 6.6e-20 amino acids 639 to 764 (126 residues), 39.8 bits, see alignment 2.2e-14 amino acids 796 to 899 (104 residues), 34.3 bits, see alignment 1.1e-12 amino acids 902 to 1023 (122 residues), 67.4 bits, see alignment 6.7e-23 PF13426: PAS_9" amino acids 406 to 506 (101 residues), 23.4 bits, see alignment 2.9e-08 amino acids 522 to 629 (108 residues), 33.1 bits, see alignment 2.9e-11 amino acids 665 to 743 (79 residues), 20.4 bits, see alignment (E = 2.7e-07) amino acids 794 to 891 (98 residues), 17 bits, see alignment 3e-06 amino acids 917 to 1018 (102 residues), 43.6 bits, see alignment 1.6e-14 PF13188: PAS_8" amino acids 516 to 568 (53 residues), 19 bits, see alignment (E = 5e-07) PF08447: PAS_3" amino acids 668 to 753 (86 residues), 65.8 bits, see alignment 1.8e-21 amino acids 800 to 882 (83 residues), 48.2 bits, see alignment 5.3e-16 amino acids 927 to 1005 (79 residues), 27.4 bits, see alignment (E = 1.6e-09) PF00989: PAS" amino acids 905 to 1013 (109 residues), 43.2 bits, see alignment 1.8e-14 PF08448: PAS_4" amino acids 910 to 1020 (111 residues), 41 bits, see alignment 9.9e-14 PF00512: HisKA" amino acids 1039 to 1104 (66 residues), 81.2 bits, see alignment (E = 2.3e-26) PF02518: HATPase_c" amino acids 1151 to 1266 (116 residues), 100.1 bits, see alignment 5.2e-32 PF00072: Response_reg" amino acids 1284 to 1392 (109 residues), 86.4 bits, see alignment 7.9e-28 amino acids 1426 to 1536 (111 residues), 91.1 bits, see alignment 2.7e-29 PF01627: Hpt" amino acids 1601 to 1674 (74 residues), 37.1 bits, see alignment (E = 1.5e-12)

Best Hits

KEGG orthology group: K00936, [EC: 2.7.3.-] (inferred from 100% identity to shn:Shewana3_3419)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0L0S3 at UniProt or InterPro

Protein Sequence (1767 amino acids)

>Shewana3_3419 multi-sensor hybrid histidine kinase (RefSeq) (Shewanella sp. ANA-3)
MDKSKLRTFRSKILSHIALPLILIMTAVYGINAWFNYLSAERKLYDSLAQESNHSAYRLQ
LLIEHAQANTQGVADFIGFISNKEGINDSEKIKRVLTNRIERNPDFYGSAVAFKPYTFPD
KKLFSPYVYRDGNNFHYLDIGAEGYDYTDGSWDWWSKAINQPGGYWSKAYFDEGAGNTLM
VTYSVPFGPENDYFGVATVDLALDKLPEQLGVQPSQLVVLDDQGRLIFHSDKEKVLAVTS
AEWLDRNTRRNSDFWTLLDKGLNGQARFIDDKSTVYLASVASVAKLKWRVIVMVPEHQLF
ATLLDDVASVVLNLSLLTLLLLLTCYIAAKRLTRPLEALESGILAFGQGKAQQLAIPKGA
VSEIVTLSSTFNQMAELLGEREQAILDSRGNRFARLIDGMSDKSFYCSLDPSGQLAQVSE
GVTKVLGMSPELLKRKYQRLFTANPLNEKNWEYTDLALKGENVPSHQVELLDASGHPRML
DLFMLPLVSDTGELMSVEMLFTDVTEQFSAATWSNAVLEAAPEAMLIVEQMGSIVFTNTR
CQILFGYDANSMLGLQVESLLPEAMRSNHARDRLQFLREGRDRPMANARHVRALKADGGE
FVAEIALSILPADHEGRRQVAASIRDMTQKLAVEQKIRDSELRFRGLVTNIPGAVYRTRI
GDVWVMEYVSDNIADITGFAASQFIENRQRTFASLILEEDRELCHQHIDRALAQQETFEV
EYRIRHRDGSIRWVHEKGKASYTEEGFPLWFDGSIDDITESKLAMVELEASRLQLTNITE
SIPCTVYQLRWVSPADHTFTFLSGAAFHMLGLHREDLLKDFNIIAERIFDEERPEVVRAL
AGKSEDKLQWVREFRYRHPNGSIRWMEAGASGHYNDDGAIIWNGYVMDITERKAIEEELA
VSEAHFKALFDGSTIGIVNVDAKGVILDCNDQYCEDMGQTRESLCGVPIFDVLSLQDKET
AKAQFRELAEGKVDHYRGERSFIRPNGEPLWMTVNVSALFDSQKQFESAVVSMVDMTELK
LLSDELLVAKEEADAASKAKGDFLANMSHEIRTPMNAIIGMSQLCLQTALDKKQKNYVEK
IERASKSLLSIINDILDFSKIEAGKLDIESVPFQLDTMLEDLSDMFSEKAAHKQLELLFA
VAPNVPRHLFGDSLRLGQVLINLMNNAIKFTERGEVLLSLNLVEQQNDDVVLRFSVRDSG
IGLTADQQAKLFKSFSQADTSTTRKYGGTGLGLAICKQLVELMGGTIGVESQFGHGSTFY
FTVKLQISSGQKLTVAQELEGMPILVADDNATARDIMRTTLESMGFRVDTVRSGEEAVTR
CIQQEYAVALIDWKMPNLDGIETAKQIKQQAKKAPRILMVSAHANQDFLSQIEELGLAGY
ISKPISASRLLDGIINSLGRAGVLPVRRQSESIDPKLLLPLKGKRILLVEDNEMNLEVAT
EFLEQVGIILSIATNGQIALDKLEQQSFDLVLMDCQMPVMDGYQATQALRKRPELTELPV
VAMTANAMAGDKEMCLRAGMNDHIAKPIEVNLLYQTLLKYLGGSASLVDNTEPSQLVDIP
VKPINLDSESVVKWPEHPELDIDRGLQLVQNSTRLYQRSFDRFVTSQRNVVDLINKALAN
DKRDDAVRMAHTLKGLAGNLSSSKLVELARQLELHLSEKSEYQTELDQIQALVASICDAI
ERVKPQFEESTTSTSEQLSPEALVTALKQLRQSLEDADSDAVAQIDALKPQVSSKLWLQL
SPALTMINQYQFDEAVDLIDEVLAELT