Protein Info for Shewana3_3402 in Shewanella sp. ANA-3

Annotation: aminopeptidase B (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF12404: DUF3663
  • amino acids 12 to 96 (85 residues), 108.9 bits, E=9.2e-36
• PF00883: Peptidase_M17
  • amino acids 112 to 424 (313 residues), 319.3 bits, E=2.9e-99

Best Hits

Swiss-Prot: 51% identical to PEPB_VIBVU: Peptidase B (pepB) from Vibrio vulnificus (strain CMCP6)

KEGG orthology group: K07751, PepB aminopeptidase [EC: 3.4.11.23] (inferred from 99% identity to she:Shewmr4_0732)

Predicted SEED Role

"Peptidase B (EC 3.4.11.23)" (EC 3.4.11.23)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.23

Sequence Analysis Tools

See A0L0Q6 at UniProt or InterPro

Protein Sequence (430 amino acids)

>Shewana3_3402 aminopeptidase B (RefSeq) (Shewanella sp. ANA-3)
MSELKVTEVMRVELTKDTPAAHWGKADVTFNAEGALVHLGGGDELRQIQMAARKLRNQGI
STVALAGALWDLNSQWVFAQGFATAKPGYKIQWCGDDAVQAELQRRLEVATFARQLINDT
PENLSPVKLAQQAAKWLADIGGAKVSYRIIEGEALLEEQWIGIHAVGRGSERPPAMLELD
FNPLSADAPVSVALVGKGITFDSGGYSIKASEGMLGMKCDMGGAATVTAALGLAIKSGLN
KRVKLFLCCAENLISGRAYKLGDILTYKNGVTVEVVNTDAEGRLVLADGLQAASATGAPF
IIDAATLTGAAVMAVGSNYNAIFSPQTEVLQLAQQKASTVAERVWPLPLDPWHKDMCPSA
YADTANSRPVKGGGAGGASNAAGFLWRFVSPEAKWLHVDLAAAFEDSASALWGAGATTHG
VLTISELIKG