Protein Info for Shewana3_3353 in Shewanella sp. ANA-3

Annotation: transketolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00456: Transketolase_N
  • amino acids 4 to 335 (332 residues), 560.1 bits, E=3.8e-172
• PF13292: DXP_synthase_N
  • amino acids 5 to 193 (189 residues), 21.5 bits, E=3.3e-08
• TIGR00232: transketolase
  • amino acids 7 to 663 (657 residues), 1023.8 bits, E=0
• PF00676: E1_dh
  • amino acids 109 to 241 (133 residues), 22.2 bits, E=1.6e-08
• PF02779: Transket_pyr
  • amino acids 355 to 525 (171 residues), 183.9 bits, E=5.2e-58
• PF02780: Transketolase_C
  • amino acids 550 to 656 (107 residues), 59.1 bits, E=1.1e-19

Best Hits

Swiss-Prot: 76% identical to TKT1_VIBCH: Transketolase 1 (tkt1) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00615, transketolase [EC: 2.2.1.1] (inferred from 100% identity to shn:Shewana3_3353)

MetaCyc: 74% identical to transketolase 1 (Escherichia coli K-12 substr. MG1655)
Transketolase. [EC: 2.2.1.1]; 2.2.1.1 [EC: 2.2.1.1]

Predicted SEED Role

"Transketolase (EC 2.2.1.1)" in subsystem Calvin-Benson cycle or Pentose phosphate pathway (EC 2.2.1.1)

MetaCyc Pathways

• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (21/26 steps found)
• pentose phosphate pathway (8/8 steps found)
• Bifidobacterium shunt (13/15 steps found)
• Rubisco shunt (9/10 steps found)
• superpathway of glucose and xylose degradation (14/17 steps found)
• Calvin-Benson-Bassham cycle (11/13 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (21/27 steps found)
• pentose phosphate pathway (non-oxidative branch) I (5/5 steps found)
• formaldehyde assimilation III (dihydroxyacetone cycle) (10/12 steps found)
• ethene biosynthesis V (engineered) (19/25 steps found)
• pentose phosphate pathway (partial) (3/3 steps found)
• pentose phosphate pathway (non-oxidative branch) II (5/6 steps found)
• oxygenic photosynthesis (12/17 steps found)
• formaldehyde assimilation II (assimilatory RuMP Cycle) (6/9 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of ansamycins
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Carbon fixation in photosynthetic organisms
• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.2.1.1

Sequence Analysis Tools

See A0L0K8 at UniProt or InterPro

Protein Sequence (664 amino acids)

>Shewana3_3353 transketolase (RefSeq) (Shewanella sp. ANA-3)
MSSRKVLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPNNPKWVDRDRF
ILSNGHGSMLIYSLLHLTGYDLPIDELKQFRQLHSKTPGHPEYGYTPGVETTTGPLGAGI
SNAVGMAIAEKTLAAQFNREGHEIVDHYTYCFLGDGCLMEGISHEACSLAGTLGLGKLIA
FWDDNGISIDGHVEGWFTDDTPKRFESYGWHVIANVDGHDSDAIRAAIEAAKAVTDKPTM
ICCKTIIGFGSPNKSGSHDCHGAPLGDAEIAAAREFLGWPHAPFEIPADVYAGWDAKEAG
NAREAAWNDKFAAYAAAYPELAAEYERRVLKGELPADFEAKAQAFIQECQAKGEGIASRK
ASQNAIAAFGAVLPELLGGSADLAGSNLTLWAGSRGIQEDPAGNYVYYGVREFGMSGIMN
GVSLHGGFINYGATFMMFMEYARNAVRMSALMGIQNIFVYTHDSIGQGEDGPTHQPVEQL
ANLRMTPNMAVWRPCDAAETAVAWKAAIERRHAPTSLVFSRQNLKAQARTAEQLANVAKG
AYVLQDCAGTPEYILIATGSEVQLAVEAAAALTEQGKQIRVVSMPSNTEFDKQDAAYKES
VLPKAVTKRIAIEAAHTDFWYKYVGFEGTVVGMTTFGESAPGNVLLKHFGFTVENVLNAA
KSLG