Protein Info for Shewana3_3064 in Shewanella sp. ANA-3

Annotation: aquaporin Z (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 38 to 62 (25 residues), see Phobius details amino acids 83 to 105 (23 residues), see Phobius details amino acids 130 to 152 (23 residues), see Phobius details amino acids 162 to 181 (20 residues), see Phobius details amino acids 206 to 227 (22 residues), see Phobius details PF00230: MIP" amino acids 3 to 224 (222 residues), 187.3 bits, see alignment E=1.8e-59 TIGR00861: MIP family channel proteins" amino acids 9 to 224 (216 residues), 203.3 bits, see alignment E=2.2e-64

Best Hits

Swiss-Prot: 94% identical to AQPZ_SHEON: Aquaporin Z (aqpZ) from Shewanella oneidensis (strain MR-1)

KEGG orthology group: K06188, aquaporin Z (inferred from 100% identity to shn:Shewana3_3064)

MetaCyc: 73% identical to water channel AqpZ (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-145

Predicted SEED Role

"Aquaporin Z"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZR9 at UniProt or InterPro

Protein Sequence (231 amino acids)

>Shewana3_3064 aquaporin Z (RefSeq) (Shewanella sp. ANA-3)
MNMSQKMAAEFLGTLWLVLGGCGSAVLAAAFPEVGIGLLGVALAFGLTVLTMAFAIGHIS
GCHLNPAVSFGLWAGGRFPASELLPYIIAQVAGGIVGAGVLYAIASGQEGFSLAAGFASN
GFGEHSPGGYSMMSVLICEIVMTLFFLLVILGATDERAPKGFAPIAIGLCLTLIHLISIP
VSNTSVNPARSTGPALFVGDWAVSQLWIFWVAPIVGAILAGMIYRYFKAAE