Protein Info for Shewana3_2984 in Shewanella sp. ANA-3

Annotation: glycosyl hydrolase family chitinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 868 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF08329: ChitinaseA_N" amino acids 27 to 158 (132 residues), 186.7 bits, see alignment E=4.2e-59 PF00704: Glyco_hydro_18" amino acids 163 to 547 (385 residues), 319.9 bits, see alignment E=8e-99 PF02010: REJ" amino acids 577 to 766 (190 residues), 30.1 bits, see alignment E=5.9e-11 PF02839: CBM_5_12" amino acids 775 to 813 (39 residues), 28.8 bits, see alignment (E = 3.2e-10) amino acids 823 to 860 (38 residues), 31.9 bits, see alignment (E = 3.3e-11)

Best Hits

KEGG orthology group: K01183, chitinase [EC: 3.2.1.14] (inferred from 100% identity to shn:Shewana3_2984)

Predicted SEED Role

"Chitinase (EC 3.2.1.14)" in subsystem Chitin and N-acetylglucosamine utilization (EC 3.2.1.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZJ0 at UniProt or InterPro

Protein Sequence (868 amino acids)

>Shewana3_2984 glycosyl hydrolase family chitinase (RefSeq) (Shewanella sp. ANA-3)
MFKTQISTSAMLVASVLASAASFQAFAALPGKPTLGWGETKFAIIEVNQAASAYNQLVTV
KDAADVSVTWNLYNGDIGNKAQVLLDGNVAWEGPSSAAGTANFKVNKGGRYQMRVQLCNN
EGCSASDAREILVADTDGSHLLPLNAPLKENNRPYANKSGKVVGSYFVEWGVYGRKFPVD
KIPAQNLTHILYGFTPICGGNGINDSLKEIEGSFEALQRACAGRADFKVAIHDPWAAVQM
PQAGVSEYSDPYKGNFGQLMALKQAYPDLKILPSVGGWTLSDPFYFLGDKTKRDTFVASV
KEFLQTWKFFDGVDIDWEFPGGSGANPSLGNANDGQTYVTLMRELRAMLDELSAETGRSY
ELTSAISAGGDKIAKVDYQAAQQYMDYIFLMSYDFNGGWTNTELGHQTNLYEASWDPNTR
YTMDKGVKALLSQGVTPGKIVVGAAMYGRGWTGVNGYSGNNPFTGTATGKVKGTWEAGVV
DYRQIAKDYMGAGWSYAYDETAEAPSVFNASTGDLITFDDARSVKAKGQYVLTNQLGGLF
AWEIDADNGDILNAMHEGLGHGEGTMPPANKAPIANAGADITVTGTADVTLNGSASRDPE
NGALSYQWSQVSGPSLSISNADMANAVVQLSEAASDVVYVFSLQVTDPEGLSSTDTVTLT
HKAETANQAPVVTVPASVTVEAGQSVSINATATDADGDSLTYAWTVPSGVAASGQNTATL
VVTAPTVTQSTQYSLSVLVSDGALDASAALTLSVTPKATGGQCDATDPNAANYPAWNATS
IYNTDDTVSYNQLVWKAKYWTQGNTPSRTADQWQLLSQVELGWDAGVAYNGGATTSYNGR
QWQAKYWTKGDVPGVAAVWTDIGAASCP