Protein Info for Shewana3_2963 in Shewanella sp. ANA-3

Name: hsdR
Annotation: type I restriction enzyme EcoKI subunit R (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1167 PF04851: ResIII" amino acids 443 to 623 (181 residues), 120.9 bits, see alignment E=1.6e-38 PF00270: DEAD" amino acids 448 to 625 (178 residues), 38.5 bits, see alignment E=3.1e-13 PF18766: SWI2_SNF2" amino acids 448 to 667 (220 residues), 57.4 bits, see alignment E=5.1e-19 PF00271: Helicase_C" amino acids 717 to 828 (112 residues), 36.8 bits, see alignment E=1.2e-12 PF08463: EcoEI_R_C" amino acids 1004 to 1164 (161 residues), 118.1 bits, see alignment E=1.3e-37

Best Hits

KEGG orthology group: K01153, type I restriction enzyme, R subunit [EC: 3.1.21.3] (inferred from 100% identity to shn:Shewana3_2963)

Predicted SEED Role

"Type I restriction-modification system, restriction subunit R (EC 3.1.21.3)" in subsystem Restriction-Modification System (EC 3.1.21.3)

Isozymes

Compare fitness of predicted isozymes for: 3.1.21.3

Use Curated BLAST to search for 3.1.21.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZH0 at UniProt or InterPro

Protein Sequence (1167 amino acids)

>Shewana3_2963 type I restriction enzyme EcoKI subunit R (RefSeq) (Shewanella sp. ANA-3)
MASSSEPSNFGFLVEHDQLFVDLANSAERAFSSDPNTTLLKLRQLGEAMAQHIAVLAGIE
FDEQTKQTDLLYRINRDLKLEPMVRELFHTLRVEGNIANHQFRTKHKEAINGLVVARKLA
IWFHQTFSKSGTAFKPGPFIPPKDPSAELFTLQAEIEGLKAQLQNANVELDSSQQLNELI
KQEKDEYEALALAMDQESKALALQAAQHEQELERVKQDYEAKLKAIQQHAKQQDDKAQRS
QLSKLSRKAFQASKAIVVDEQLTRILIDQQLNEAGWTADTQTIRYSSNSRPEKGKYKAIA
EWPTSTGNADYVLFAGLTPIVVVEAKRENINVAGKISQAERYSRSIKIKGECDWAWEVAG
RTVAWPDEQESHYKVPFVYSCNGRPYVPQLAEQSGTWFRDVRDPSNLKRALPSFHTPTGL
LDLLNRSKEEAQVKLQQEPFGYLKLRDYQIKAIEAVESVLSQNVRSALLAMATGTGKTRT
IIGLIYRFLKAERFKRVLFLVDRFALGDQAQNDFKEVSLEQNLSLSGIYNIAELGDMAAE
AETRIQVSTVQAMVKRVFMSDNPPPLDQFDCIIVDEAHRGYTLDQEMTEGEIATRDAAQY
LSSYRRVLDYFDAVKIALTATPAKHTSEIFGKPVYTYSYREAVAEDWLIDHEPPIRYETL
LTQNGISFTKGETVSAINTQTGEIESAELEDELNFEVEAFNRCVINENFNKVICEQLVQE
LDPFGDEKTLIFCATDLHADMVKRLLDDAFKAIYNGEYNQAAVAKITGQSDKVNQLIKQY
KNERYPNIAITVDLLTTGIDVPKICNLVFMRRVKSRILYEQMIGRATRRCDDIGKTVFRI
YDPVDIYAALSDVNTMNPLVKDPNVTIEQLIDELSDPESLERALNAPGEQQGETQADVVL
TQLGQKVMRILRKAAKKAEAKPELKQKLDELQDLWGVEPKNLHTHLRQLGPKDASVFINQ
HAGLLKQLAEVNSLLGSEYQPIISEHEDELRERTQSYGTHQRPEDYLQGFEHFIREQINQ
SAALAVVVNRPRDLTRGQLKEIKLLLDAAGYTEASLQTAVRNQTNQEIAASIIGHIRRAA
MGEALIPFEQRVAKAMEYIYASHPWTPVQRKWLEKLAKQLKNEVVLDQQFINQRFRDDGG
VKGVNNRLGNHLDEVLDELKQHLWEAS