Protein Info for Shewana3_2908 in Shewanella sp. ANA-3

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 189 PF02589: LUD_dom" amino acids 80 to 189 (110 residues), 52.6 bits, see alignment E=2.5e-18

Best Hits

KEGG orthology group: K00782, hypothetical protein (inferred from 99% identity to she:Shewmr4_2738)

MetaCyc: 96% identical to L-lactate dehydrogenase LldF subunit (Shewanella oneidensis)
L-lactate dehydrogenase (cytochrome). [EC: 1.1.2.3]

Predicted SEED Role

"Predicted L-lactate dehydrogenase, hypothetical protein subunit SO1518" in subsystem Lactate utilization

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.2.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZB6 at UniProt or InterPro

Protein Sequence (189 amino acids)

>Shewana3_2908 hypothetical protein (RefSeq) (Shewanella sp. ANA-3)
MSSKHEILNALKLSALTNHPMPSIDVAPRVEDLVGQFETNLKTVAGTLHREGGLVALQAK
VDELVAQGLQVISLVEGVTANREVPPTAHELRDIDYAVIPGDVGVAENGAIWVNNKNLGH
RVTPFICENLILALPSTKIVPNMHQAAKDITLDAGEFGVFIAGPSKTADIEQALVVGAHG
ACSLNVYLV