Protein Info for Shewana3_2884 in Shewanella sp. ANA-3

Annotation: diguanylate cyclase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 PF20975: DGCcoil" amino acids 1 to 339 (339 residues), 461.9 bits, see alignment E=1.6e-142 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 355 to 516 (162 residues), 152.7 bits, see alignment E=3.7e-49 PF00990: GGDEF" amino acids 359 to 513 (155 residues), 149.6 bits, see alignment E=7.1e-48

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2884)

Predicted SEED Role

"GGDEF domain family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KZ92 at UniProt or InterPro

Protein Sequence (518 amino acids)

>Shewana3_2884 diguanylate cyclase (RefSeq) (Shewanella sp. ANA-3)
MKDSNTTVSQLALLQQKLHSAKLALDEVNEDRNAKLQTLLQFIGHLSLACKGQNLELDNK
LAKLRHNLNTFERVDEALPELVDVERLLKGQYHHVMVQLEESRTGLAQVIRQIQRVNSAP
DKLKKEVNYFKQDLAKPFHTVWEYIPKVKQIIGFYDTILQQQFEEAEKLDVLPKHRQLAH
ELAQMISEIEFRKDQRDQVLVIKELLASEVEIDTLLEAYQTILSLLLDNIAREKSASQEF
LYALNDALAAVREVVSESYNHNQRSFQLKTQLNREINSRVDNVGEAIIDTDDIVDLKAQL
TEQLSSIRSALARKEALEQREQALLRKSMETMRKELNELSSEANTYKERLFEQQKLNLLD
SLTQLPNRAALEERMELEYRNYQRHRTPLWIAVADIDHFKSINDSFGHSTGDKTLQVIAM
ALKNSLRDTEFVARYGGEEFVLILPEIDGGDIAQLLNRVREKVKNIPFKFKNQRITVTVS
IGAAQVMGNELIHETFERADAALYKAKHESRDRVVIDV