Protein Info for Shewana3_2707 in Shewanella sp. ANA-3

Annotation: phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 45 to 181 (137 residues), 145.7 bits, E=1.4e-46
• PF02879: PGM_PMM_II
  • amino acids 219 to 317 (99 residues), 86.3 bits, E=3.8e-28
• PF02880: PGM_PMM_III
  • amino acids 326 to 443 (118 residues), 54.1 bits, E=3.2e-18
• PF00408: PGM_PMM_IV
  • amino acids 490 to 541 (52 residues), 30.8 bits, 5.1e-11

Best Hits

KEGG orthology group: K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 100% identity to shn:Shewana3_2707)

Predicted SEED Role

"Phosphomannomutase (EC 5.4.2.8) clustering with Aga operon" (EC 5.4.2.8)

MetaCyc Pathways

• GDP-mannose biosynthesis (2/4 steps found)
• β-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation (1/3 steps found)
• colanic acid building blocks biosynthesis (6/11 steps found)
• β-(1,4)-mannan degradation (1/7 steps found)
• superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis (4/14 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.8

Sequence Analysis Tools

See A0KYR5 at UniProt or InterPro

Protein Sequence (573 amino acids)

>Shewana3_2707 phosphoglucomutase/phosphomannomutase alpha/beta/subunit (RefSeq) (Shewanella sp. ANA-3)
MNTHLQLQVKHWLENDPDPRTQAQLQALIDAGNDAELEARFAGRLEFGTAGLRGVVGAGP
MGMNRLVIRQTSAGLGAYLLEQIKDAAERGVVIGYDGRHDSRTFAHDTASVLTAMGIKVR
LTAKVAPTPLVAFGVKHFNAAAGIVVTASHNPPQYNGYKVYWENGAQIIPPHDSGIAAKI
ELAATQAIPFMDQVEATKQGKLIWLQDDYYETYRRGVMHANVLQNNTAPEKVSLAYTAMH
GVGAEMAETVLKDAGFAQVYSVVAQREPDGDFPTVNFPNPEEKGAMDLVIAEAKKHGAML
ACANDPDADRFAVAVRKDDGEYQMLTGDQVGVLFGHYLLSHASKEQRLVGTTIVSSSLLS
KIAKGFGVESYTTLTGFKWLMNVGIAQSQPDNQFLFAYEEALGYTVGNMVWDKDGLSALV
AFAQLTAELAAKGQTIWDRLEQIYREQGFHLNAQVSIALKPDTPNIGAYLREHPPLAIGE
HALVSTDDLKALERRFADGKVEKINLPASDVLTYRLANGARVIVRPSGTEPKIKCYYEVV
EPMTAQDTLASAQARATLAMEAFISAHQASLPK