Protein Info for Shewana3_2698 in Shewanella sp. ANA-3

Annotation: N-acetylglucosamine kinase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00480: ROK
  • amino acids 2 to 297 (296 residues), 218.8 bits, E=1.2e-68
• PF02685: Glucokinase
  • amino acids 6 to 252 (247 residues), 47.9 bits, E=9.8e-17

Best Hits

Swiss-Prot: 100% identical to AGAK_SHESA: N-acetylgalactosamine kinase AgaK (agaK) from Shewanella sp. (strain ANA-3)

KEGG orthology group: K00884, N-acetylglucosamine kinase [EC: 2.7.1.59] (inferred from 100% identity to shn:Shewana3_2698)

MetaCyc: 100% identical to N-acetylgalactosamine kinase (Shewanella sp. ANA-3)
2.7.1.-

Predicted SEED Role

"N-acetylgalactosamine kinase, ROK-type (EC 2.7.1.157)" in subsystem N-Acetyl-Galactosamine and Galactosamine Utilization (EC 2.7.1.157)

MetaCyc Pathways

• N-acetylglucosamine degradation II (3/3 steps found)
• N-acetyl-D-galactosamine degradation (4/5 steps found)
• chitin derivatives degradation (3/8 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.59

Use Curated BLAST to search for 2.7.1.157 or 2.7.1.59

Sequence Analysis Tools

See A0KYQ6 at UniProt or InterPro

Protein Sequence (308 amino acids)

>Shewana3_2698 N-acetylglucosamine kinase (RefSeq) (Shewanella sp. ANA-3)
MYYGLDIGGTKIELAIFDTQLALQDKWRLSTPGQDYSAFMATLAEQIEKADQQCGERGTV
GIALPGVVKADGTVISSNVPCLNQRRVAHDLAQLLNRTVAIGNDCRCFALSEAVLGVGRG
YSRVLGMILGTGTGGGLCIDGKLYLGANRLAGEFGHQGVSANVACRHQLPLYVCGCGLEG
CAETYVSGTGLGRLYQDIAGQTADTFAWLNALRCNDPLAIKTFDTYMDILGSLMASLVLA
MDPDIIVLGGGLSEVEEILAALPQATKAHLFDGVTLPQFKLADFGSASGVRGAALLGHGL
DAGISYEA