Protein Info for Shewana3_2681 in Shewanella sp. ANA-3

Annotation: vibriolysin (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF07504: FTP" amino acids 44 to 86 (43 residues), 23.7 bits, see alignment 7.2e-09 PF03413: PepSY" amino acids 104 to 173 (70 residues), 28.1 bits, see alignment E=4.1e-10 PF01447: Peptidase_M4" amino acids 210 to 348 (139 residues), 125.5 bits, see alignment E=4.6e-40 PF02868: Peptidase_M4_C" amino acids 351 to 497 (147 residues), 131.5 bits, see alignment E=5.8e-42

Best Hits

KEGG orthology group: K08604, vibriolysin [EC: 3.4.24.25] (inferred from 100% identity to shn:Shewana3_2681)

Predicted SEED Role

"Vibriolysin, extracellular zinc protease (EC 3.4.24.25) @ Pseudolysin, extracellular zinc protease (EC 3.4.24.26)" (EC 3.4.24.25, EC 3.4.24.26)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.25 or 3.4.24.26

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KYN9 at UniProt or InterPro

Protein Sequence (500 amino acids)

>Shewana3_2681 vibriolysin (RefSeq) (Shewanella sp. ANA-3)
MKVYLLPSAVAVCIAASLQAQAVEIKVNHGQSLSAAAGLSQQHSFKAIKTVTFNKGQTKT
KALQYFNGVLVYGHHLVVSNDDSEQSAIGDVAQIADDFSVEAGISQGQAIAALNRLYPGS
AATGKKDVELVILMQDDTPRLVYRVSYLSDQTDALSRPTGFVDAQTGEVLEHWNEIMTAK
NNVGKPGSGGGGSGGSSNPFDATGPGGNAKIGDYYYGSDYGFLKVSESNGTCTMTNANVK
TVNMANSTRRGSVFTFTCPENTYQTVNGAYSPLNDAHYFGGVIFNMYKDWYNTAPLTFQL
EMRVHYGRNYENAFWDGSAMSFGDGASYFYPLVSLDVSAHEVSHGFTEQNSGLNYSGQSG
GINEAFSDIAGEAAEFYMRGSNDWKVGYDIVKGNGALRYMDNPTKDGRSIDNAANYTSSM
DVHYSSGVFNKAFYTLATKNGWDTRKAFDVFVLANQLYWTPTSTFNKAACGVQQAASAKG
SGYPVADVAAAFLAVGVICQ