Protein Info for Shewana3_2621 in Shewanella sp. ANA-3

Annotation: TPR repeat-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF28559: TPR_SusR" amino acids 43 to 141 (99 residues), 34.6 bits, see alignment E=8.5e-12 PF13424: TPR_12" amino acids 83 to 142 (60 residues), 35.1 bits, see alignment E=6.9e-12 PF13432: TPR_16" amino acids 85 to 144 (60 residues), 23 bits, see alignment E=4.8e-08 amino acids 330 to 385 (56 residues), 20.2 bits, see alignment 3.7e-07 PF13181: TPR_8" amino acids 85 to 110 (26 residues), 19.8 bits, see alignment (E = 3.7e-07) amino acids 327 to 355 (29 residues), 13.6 bits, see alignment (E = 3.4e-05)

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2621)

Predicted SEED Role

"TPR domain protein, putative component of TonB system" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KYH9 at UniProt or InterPro

Protein Sequence (415 amino acids)

>Shewana3_2621 TPR repeat-containing protein (RefSeq) (Shewanella sp. ANA-3)
MRNANKIAVALLLSLCGGALSVSSAVAAEKCEIDKRQSKAVGESAAKKVQKSFEAYTNGQ
LDEAIAVLLEANPKNDFDKAYVARMLGNFYAEKGKMDTAIKYLKQAVEADILGGTDHAAT
LRLYADLLLQEKKFKEAIPYYYKWMDFTCKADSQMYRRIGIAYTELKQWDKVIEVADKGL
SLAEAPDKGLYQMKLTSYFNQKKYKKAVGVLEVMVPLFPDDGRLWVQLAQFYLMVEDYDK
SLATYDLAYRNGFLDSGANITRLAQLMAQKGAPYQAAKVFQKNMKSGLITEDAKSYEILA
GFYQNAKEFKEAAEFYGKAAAINNDGKLYLKQGRLLSLNEKYSEAIPVLEKAISLGIEHP
GEANFELALAHLSLKQYKSAYNRAVLAAKDKKTEKSANSYIAYIKEKARMHNVEL