Protein Info for Shewana3_2501 in Shewanella sp. ANA-3

Annotation: cyclic nucleotide-binding protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 226 PF00027: cNMP_binding" amino acids 35 to 117 (83 residues), 41.7 bits, see alignment E=9.1e-15 PF13545: HTH_Crp_2" amino acids 180 to 220 (41 residues), 29 bits, see alignment 8.7e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2501)

Predicted SEED Role

"Predicted N-ribosylNicotinamide CRP-like regulator" in subsystem NAD and NADP cofactor biosynthesis global or PnuC-like transporters

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KY61 at UniProt or InterPro

Protein Sequence (226 amino acids)

>Shewana3_2501 cyclic nucleotide-binding protein (RefSeq) (Shewanella sp. ANA-3)
MQLKPLAKGRYSQRWEQDYPLIEAVILSCISEIKMLKKGAHLMTQGEAINSLVLVKQGRV
SLGHTARNGRCFQLGTIDCDSQLFGEMEFFTQYQCQLDIIASEPLEISLISNEKLQHSLG
QHPQLALFFASAIAIDYQDTVDIFTRRLLYPISYNVAFDIYHEYLNDLPVDGFSKRYLEA
ERFGTTDRVYRRALQHLEERGLIERKKEGIRIKNLDALKAFVEAGI