Protein Info for Shewana3_2252 in Shewanella sp. ANA-3

Annotation: LacI family transcription regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 346 PF00356: LacI" amino acids 9 to 49 (41 residues), 52.8 bits, see alignment 5.3e-18 PF00532: Peripla_BP_1" amino acids 81 to 321 (241 residues), 75.7 bits, see alignment E=8.9e-25 PF13407: Peripla_BP_4" amino acids 82 to 321 (240 residues), 41 bits, see alignment E=3.5e-14 PF13377: Peripla_BP_3" amino acids 179 to 338 (160 residues), 116 bits, see alignment E=4e-37

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2252)

Predicted SEED Role

"Transcriptional regulator of maltose utilization, LacI family" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KXG2 at UniProt or InterPro

Protein Sequence (346 amino acids)

>Shewana3_2252 LacI family transcription regulator (RefSeq) (Shewanella sp. ANA-3)
MASKATSIDIAYRAGVSQSTVSRALRNSPLVNLETRQRIQAIAKELNYKVDKNASNLRTQ
NSHTLALLLCEDPTNDDSLINPFFLSMLGSITRATAQQGYDLLVSFQQLSSDWHADYEDS
NKADGIILLGYGDYMDYEQKLEKLLAQNTHFVIWGAEHNNKSVLSIGCDNHQGGLIATEH
LISLGRKDFAFLGGASSHCPEFRDRYLGHVKALQTAGLTVDPRRQISAISTEGAGYYATL
ELLDKGLNFDAIFAASDLIAIGAIRALKEKGILVPEQVAVVGYDDIPVASFANPPLTTIK
QNTQLAGEILVESLLKLIRGQAVSPQLIPTTLVVRSSCGIDCTPLA