Protein Info for Shewana3_2186 in Shewanella sp. ANA-3

Annotation: Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit-like protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 176 transmembrane" amino acids 80 to 102 (23 residues), see Phobius details PF21980: MksE" amino acids 6 to 168 (163 residues), 34.9 bits, see alignment E=9.9e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to shn:Shewana3_2186)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KX96 at UniProt or InterPro

Protein Sequence (176 amino acids)

>Shewana3_2186 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit-like protein (RefSeq) (Shewanella sp. ANA-3)
MFASRLIYKDFIAGAVINKYEVIEGELQSSQKFRALIDDIDKYRYVYSLLGFTIQSIGEE
SFFVTRTDRAEEYNEVAANIQVLLLVILRGVYSLGIAPGILLDPTAGLSRMQIDDIGNIN
EQKRILEACKMKLPLSESVNSLLVNRGICFKTKSDRYILSAAGKYLFQQLTASANL