Protein Info for Shewana3_2147 in Shewanella sp. ANA-3

Annotation: deoxyguanosinetriphosphate triphosphohydrolase-like protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 446 TIGR01353: putative dGTPase" amino acids 21 to 433 (413 residues), 408.9 bits, see alignment E=1.6e-126 PF01966: HD" amino acids 59 to 132 (74 residues), 29 bits, see alignment E=1.2e-10 PF13286: HD_assoc" amino acids 339 to 430 (92 residues), 91.6 bits, see alignment E=3.7e-30

Best Hits

Swiss-Prot: 100% identical to DGTL1_SHESA: Deoxyguanosinetriphosphate triphosphohydrolase-like protein (Shewana3_2147) from Shewanella sp. (strain ANA-3)

KEGG orthology group: K01129, dGTPase [EC: 3.1.5.1] (inferred from 100% identity to shm:Shewmr7_1933)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KX58 at UniProt or InterPro

Protein Sequence (446 amino acids)

>Shewana3_2147 deoxyguanosinetriphosphate triphosphohydrolase-like protein (RefSeq) (Shewanella sp. ANA-3)
MSSSVWQERRHGEDKQRRNDHRSPFQRDRARILHSAAFRRLQAKTQVLGVGMNDFYRTRL
THSLEVSQIGTGIAAQLSRKYPEHKPLLGSMSLLESLCLAHDIGHPPFGHGGEVALNYMM
RHHGGFEGNGQTFRILSKLEPYTEAFGMNLCRRTMLGILKYPASQSLLFVAGSHPEITNH
RQLKPSQWPPVKGIFDDDSDIFDWVLEPLSVADRARFTSVQPSLQPNYPHLRTQFKSFDC
SIMELADDIAYAVHDLEDAIVMGIVTASQWQQDVAPTLKHSGDPWIRQELADIGTKLFSH
EHHLRKDAIGTLVNGFVTAIIINDDPAFEEPLLRFNASLEPEFANALNVLKQLVFKYVIR
KPEIQMLEYKGQQIVMGLFEAFASDPERLLPLNTQERWRTSEQQGQNSHRVLADYISGMT
DEFAGRLYQQLFSPKAGSNVELSKEM