Protein Info for Shewana3_2074 in Shewanella sp. ANA-3

Updated annotation (from data): L-arabinose ABC transporter, ATPase component AraV
Rationale: Specifically important for L-arabinose utilization; the gene name is from PMC2996990
Original annotation: ABC transporter related (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 PF00005: ABC_tran" amino acids 20 to 169 (150 residues), 99 bits, see alignment E=3.6e-32 amino acids 275 to 428 (154 residues), 71.6 bits, see alignment E=1e-23

Best Hits

Swiss-Prot: 47% identical to FRUK_BIFLO: Fructose import ATP-binding protein FruK (fruK) from Bifidobacterium longum (strain NCC 2705)

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 100% identity to shn:Shewana3_2074)

MetaCyc: 54% identical to galactofuranose ABC transporter putative ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-491 [EC: 7.5.2.9]; 7.5.2.9 [EC: 7.5.2.9]

Predicted SEED Role

"Predicted L-arabinose ABC transport system, ATP-binding protein" in subsystem L-Arabinose utilization

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0KWY5 at UniProt or InterPro

Protein Sequence (499 amino acids)

>Shewana3_2074 L-arabinose ABC transporter, ATPase component AraV (Shewanella sp. ANA-3)
MSLILELKQISKHYPGVKALEDVSLRLFAGEVHALLGENGAGKSTLVKVMTGAQSKDMGD
ILFLGEPQHFNTPMDAQKAGISTVYQEVNLVPNLTVAQNLFLGYEPRRLGLIHFKKMYAD
ARAVLTQFKLDIDVSAPLSDYSIAVQQLIAIARGVAMSAKVLVLDEPTASLDAKEVQVLF
GILNQLKAKGVAIVFITHFLDQVYQISDRITVLRNGQFIGEYLTAELPQPKLIEAMLGRS
LQEQLVDKQEKERTVTRAEAVLLSLEDVSVKGSIQSMNLTVPKGQAVGLAGLLGSGRSEV
CNAVFGLDLVDSGSIHLAGQKLNLSQPVDAISAGIALCPEDRKIDGIIGPLSIRENIILA
LQARIGWWRYLSNTRQQEIAQFFIDKLQIATPDADKPIEQLSGGNQQKVILARWLAIEPI
LLVLDEPTRGIDIGAHAEIVKLIRTLCDEGMSLLVASSELDELVAFSNKVVVLRDRYAVR
ELSGAELTSQHVMQAIAEG